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Nathan Singh proslijedio/la je TweetHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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Nathan Singh proslijedio/la je Tweet
Impaired death receptor signaling in leukemia causes antigen-independent resistance by inducing CAR T cell dysfunction | Cancer Discoveryhttps://cancerdiscovery.aacrjournals.org/content/early/2020/01/24/2159-8290.CD-19-0813 …
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Nathan Singh proslijedio/la je Tweet
New paper from UPenn's
@MarcoRuella@GillSaar@NathanSinghLab1 proposing an explanation for primary resistance to (at least CD19) CAR Ts Impaired death receptor signaling in leukemia causes antigen-independent resistance by inducing CAR T cell dysfunction https://cancerdiscovery.aacrjournals.org/content/early/2020/01/24/2159-8290.CD-19-0813 …pic.twitter.com/yk2nrXrMLe
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Nathan Singh proslijedio/la je Tweet
Resistance to
#CART - it’s your#cancer stupid: Impaired death receptor signaling in leukemia causes antigen-independent resistance by inducing CAR T cell dysfunctionhttps://cancerdiscovery.aacrjournals.org/content/early/2020/01/24/2159-8290.CD-19-0813 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Nathan Singh proslijedio/la je Tweet
Resistance to CAR-T? It's your cancer, not your immune system — study – Endpoints News
@CD_AACR @NathanSinghLab1 @MarcoRuella @RuellaLab @PennMedicinehttps://endpts.com/resistance-to-car-t-its-your-cancer-not-your-immune-system-study/ …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Nathan Singh proslijedio/la je Tweet
Online today in
@CD_AACR: Impaired death-receptor signaling in#leukemia causes antigen-independent resistance by inducing CAR-T cell dysfunction@NathanSinghLab1@MarcoRuella@RuellaLab@PennMedicine@WUSTLmed#immunotherapyhttps://cancerdiscovery.aacrjournals.org/content/early/2020/01/24/2159-8290.CD-19-0813 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Nathan Singh proslijedio/la je Tweet
Just published! Impaired death-receptor signaling in
#leukemia causes antigen-independent resistance by inducing CAR-T cell dysfunction@NathanSinghLab1@MarcoRuella@RuellaLab@PennMedicine@WUSTLmed#immunotherapy https://cancerdiscovery.aacrjournals.org/content/early/2020/01/24/2159-8290.CD-19-0813 …pic.twitter.com/HRBiQePGjT
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Nathan Singh proslijedio/la je Tweet
Why is tox lower in
#realworldevidence of#tisagenlecleucel /#Kymriah in ALL? - better management? - earlier Toci? - but especially earlier referral and fewer patients with highly refractory disease@NovartisCancer@PedCancerCarehttps://twitter.com/VJHemOnc/status/1222953898438250499 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
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Nathan Singh proslijedio/la je Tweet
In this study, we discovered that impaired death receptor signaling in leukemia causes antigen-independent resistance to CAR T cells by causing T cell dysfunction.
@NathanSinghLab1@GillSaar@RuellaLab@carlhjune@PennMedicine@CD_AACR@NovartisNewshttps://cancerdiscovery.aacrjournals.org/content/early/2020/01/24/2159-8290.CD-19-0813 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
So excited to share our paper from my time with
@carlhjune out now in@CD_AACR! Ton of collaborative work: thanks to@MarcoRuella, Saar Gill,@WeitzmanLab,@NovartisScience and others@PennMedicine. Check it out!https://cancerdiscovery.aacrjournals.org/content/early/2020/01/24/2159-8290.CD-19-0813 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
More killer work coming out of the Mackall lab about
#CARTcell dysfunction. Congrats@EvanWeberPhD@Satpathology and all the other stars on this exciting paper!https://twitter.com/EvanWeberPhD/status/1221926196251783168 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Nathan Singh proslijedio/la je Tweet
The 1st International Conference on Base Editing is kicking off now in beautiful Palm Springs. Thank you Reuben Harris, Catriona Jamieson, Alexis Komor, Branden Moriarity, and Matt Weitzman for organizing!


#Deaminet2020pic.twitter.com/Lti1DSEeqQ
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Nathan Singh proslijedio/la je Tweet
Met-Flow: interrogation of active metabolic pathways in individual T cells by flow cytometry. Should try on pre-infusion vs f/up samples. Very cool.
@hotirishmonkeyhttps://www.biorxiv.org/content/10.1101/2020.01.21.914663v1 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Nathan Singh proslijedio/la je Tweet
Glypican-3-specific CAR T cells co-expressing IL15 and IL21 have superior expansion and antitumor activity against hepatocellular carcinoma https://cancerimmunolres.aacrjournals.org/content/early/2020/01/17/2326-6066.CIR-19-0293 …
@TCHResearchNews@BCMCancerCenter#livercancer#Cancer@AACRHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Nathan Singh proslijedio/la je Tweet
Sure. In neuroscience. I mean is there anything more truly hard to grasp than how some members of a species can produce incredible art, music, poetry, writing and science, while others emit unmitigated bullshit like this?https://twitter.com/drmichaellevin/status/1216162589006278661 …
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Nathan Singh proslijedio/la je Tweet
Pleased to announce my appointment for 2020 as Chair of the
@FACTunmc Professional Relations Committee http://www.factwebsite.org/ pic.twitter.com/hpF7UzRVSj
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Nathan Singh proslijedio/la je Tweet
Cardiovascular Events Among Adults Treated With Chimeric Antigen Receptor T-Cells (CAR-T) | JACC: Journal of the American College of Cardiologyhttp://www.onlinejacc.org/content/74/25/3099 …
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Nathan Singh proslijedio/la je Tweet
2020 will be the decade of cell therapy and genome engineeringhttps://twitter.com/BLLPHD/status/1212454696381751296 …
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New review about mechanisms of
#CARTcell failure out in Seminars in Cancer Biology! Great fun writing it with@PennMedicine and@Novartis colleagues. Lots of work to do to improve this platform!https://www.sciencedirect.com/science/article/pii/S1044579X19303980?via%3Dihub …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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