Interesting. So Rapamycin and Everolimus activate AMPK, much as Metformin does. I guess it makes sense, AMPK activation is a catabolic conservative processes and mTOR inhibition mimics that.
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«Our findings reveal fundamental bidirectional regulation between two major metabolic signalling *networks* and uncover new opportunities for cancer treatment strategies aimed at suppressing cell proliferation in the nutrient-poor tumour microenvironment.»
#systemsbiology - Još 1 odgovor
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Very interesting paper!
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