How should we create knowledge?
We know "The Scientific Method" well: we ask questions then seek answers.
But what about having many answers, and no questions?
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Paper summary + more)pic.twitter.com/OWPhVTmxab
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We lose a lot by ignoring inductive methods. Inductive methods give us the freedom to look at the system as a whole and deduce insights we might not have constructed otherwise.pic.twitter.com/ybhQGoZsiQ
Example: Molecular vs. Systems Biology on Genes Molecular biologists would seek gene functions, then find the genes. Systems biologists would start with all data. It turned out that the former missed 40% of uncovered genes, because they were geared on functions only.pic.twitter.com/q8YrVgIkdK
So much has happened since 2003. We have computational power that enable us navigate different flavors of big data. We even have the capacity to automate some hypotheses discovery. Data science evolved and formalized as a proactive arm that unearths insights from big data.
Takeaway message: We need both hypothesis-driven and data-driven sciences. They are complementary. Data-driven science is laden with assumptions, but it help us view the system as a whole. [paper: https://cpb-us-w2.wpmucdn.com/sites.gsu.edu/dist/d/2411/files/2017/10/Kell_et_al-2004-BioEssays-1sin81j.pdf …]pic.twitter.com/Iua4d0ecOJ
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