interesting in vivo results from ivermectin, a very interesting drug. Original article is here: https://www.sciencedirect.com/science/article/pii/S0166354220302011 …. ivermectin is more exotic than hydroxychloroquine, not likely to be used much for months and thus far not praised by Trump. Thus good chance CDC will support.https://twitter.com/SergeiMillian/status/1246473420432424960 …
And that's best case, assuming perfect absorption and distribution. Compare also to peak blood levels observed when given a dose of 0.165 mg/kg: they were about 50 ng/mL, which is 0.050 mg/liter, about a factor of 100 lower than eradication level.https://www.rxlist.com/stromectol-drug.htm …
-
-
That web page also lists toxic levels: "Significant lethality was observed in mice and rats after single oral doses of 25 to 50 mg/kg and 40 to 50 mg/kg, respectively." A bit higher, probably, than coronavirus-lethal doses, but not much headroom there.
-
Someone raised the prospect of inhalation to specifically target lungs
End of conversation
New conversation -
Loading seems to be taking a while.
Twitter may be over capacity or experiencing a momentary hiccup. Try again or visit Twitter Status for more information.

