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NEJM
@NEJM
The New England Journal of Medicine (NEJM.org) is the world’s leading medical journal and website.
Boston, MANEJM.orgJoined March 2009
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NEJM
@NEJM
New editorial by Steven R. Cummings, M.D., and Clifford Rosen, M.D.: "The VITAL Trial: A Decisive Verdict about Vitamin D Supplementation" nej.md/3oEyOsc
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NEJM
@NEJM
With policymakers targeting members of sexual and gender minority groups, the health care sector can mitigate resulting harm and advocate for evidence-based policies protecting health and well-being. nej.md/3OEnQO0
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NEJM
@NEJM
A 23-year-old man presented with double vision and eyelid drooping on the right side that worsened at the end of the day. The neurologic examination showed ptosis on the right side and "curtain sign." nej.md/3ovwST4
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@NEJM
Health law shapes the landscape of health care delivery in powerful ways. The history of health law can be broken into four eras, each with its own prevailing ethos. nej.md/3cyWagb
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NEJM
@NEJM
A 68-year-old woman living in Japan presented with a 5 day history of fevers, myalgias, and petechial rash spreading on her arms, trunk, palms and soles. On exam, there was also an eschar on the right medial ankle. Which is the most appropriate treatment? nej.md/3OCuDbe
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NEJM
@NEJM
A combination of brentuximab vedotin plus doxorubicin, vinblastine, and dacarbazine has been shown to improve progression-free survival in Hodgkin's lymphoma. Data on overall survival are needed. New research findings are summarized in a short video. nej.md/3BciZAQ
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@NEJM
Primary care practices are increasingly taking on accountability for total health care spending for a defined population. Such arrangements could have implications for clinicians and patients. nej.md/3PXv6Wy
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NEJM
@NEJM
A 59-year-old woman with a history of smoking tobacco presented with a 5-month history of darkening of the skin on her palms. Velvety thickening on the palms and fingers was observed on physical examination. nej.md/3zCqpvT
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@NEJM
A 49-year-old man with a family history of diabetes was evaluated because of hypoglycemia. Two hours earlier, he had been found on the floor, obtunded and making nonpurposeful movements. A diagnostic test was performed. nej.md/3BgjtG2
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@NEJM
Smoking addiction causes substantial illness and death; morbidity and mortality are markedly reduced with cessation. Effective treatments for smoking addiction include medications and counseling. nej.md/3BhG5WF
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@NEJM
The editors are joined by ACTG Chair Judy Currier, M.D., to discuss the evolving role of research groups in combatting Covid-19 and future epidemics. nej.md/3QgFbOz
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NEJM
@NEJM
Rare mutations in CIDEB protect against liver disease, making the gene a candidate target for treatment. Suppression of CIDEB interferes with the formation of fat droplets in cells. nej.md/3PPjRzk
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NEJM
@NEJM
Litifilimab, a blood dendritic cell antigen 2 antibody, was superior to placebo with regard to a measure of disease activity in cutaneous lupus erythematosus at 16 weeks. nej.md/3Q0jKAU
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@NEJM
A study ancillary to a large trial showed that supplemental vitamin D3 did not lower the risk of fractures among generally healthy midlife and older adults not selected for vitamin D deficiency, low bone mass, or osteoporosis. nej.md/3z3O8DI
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@NEJM
Among patients with triple-negative breast cancer and high expression of PD-L1, pembrolizumab plus chemotherapy resulted in longer overall survival than chemotherapy alone. New research findings are summarized in a short video. nej.md/3ofViQl
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@NEJM
A resident who faces devastating personal loss at the start of the Covid pandemic embraces the theory that grief doesn’t get smaller over time: our lives grow bigger around it. nej.md/3PmAoL8
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@NEJM
Some foundational behavioral-science principles can enable health professionals to use statistics about the health effects of climate change in ways that inform and promote action. nej.md/3PmqWYm
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NEJM
@NEJM
A 78-year-old man with type 2 diabetes presented with hemiballism of the left arm and leg. Evaluation revealed hyperglycemia and an area of increased density in the right basal ganglia on imaging. nej.md/3IRy8cv
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@NEJM
A 23-year-old man presented with a 1-month history of double vision and right eyelid drooping that worsened at the end of the day. What is the most likely diagnosis? nej.md/2Ku5WxD
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@NEJM
Hemophilia B is a bleeding disorder caused by mutations in the F9 gene that lead to low clotting factor IX levels. Gene therapy to restore factor IX levels might provide long-term treatment. New research findings are summarized in a short video. nej.md/3aMFZLT
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@NEJM
Data from Singapore showed that during a period when the omicron variant was predominant, BNT162b2 vaccination reduced the risks of SARS-CoV-2 infection and Covid-19–related hospitalization among children 5 to 11 years of age. nej.md/3RLudCc
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@NEJM
A 26-year-old woman presented with sore throat, pain while swallowing, shortness of breath, and fever. Marked swelling of the posterior oropharynx was observed on physical examination, and CT of the neck was performed. nej.md/3AYvCze
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