1/ all of the data that I've read shows that they do significantly reduce both infection and transmission, over noticeable lengths of time. Yes, I have seen 1 or 2 outlier studies that show that reduction of infection/transmission falls very low after a year or so but I doubt it https://twitter.com/green_groacer/status/1436346611144138754 …
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7/ > quickly waning efficacy. I am entirely open minded on this topic. However, people bring it up all the time as a non sequitur. A: "vaccines reduce risk of catching and transmitting covid" B: "efficacy drops over time" uh...even if true, so? https://twitter.com/green_groacer/status/1436349473777618947 …
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8/ "what can be forced" is 100% orthogonal to my topic I refuse to debate policy ; politics is the mind killerhttps://twitter.com/bkidd942/status/1436351018544115714 …
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9/ Linking to a study you recommend is useful. Saying something like this is useless. https://twitter.com/andrewsiff/status/1436351200732098563 …
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yeah possibility of risk compensation is often going to be a problem interpreting this stuffhttps://twitter.com/mormo_music/status/1426516988902391812?s=19 …
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incidentally: we could look for correlation between booster rollout and downturn in spread. if that happens then it seems less likely that risk compensation is responsible for apparent waning
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CD8+ and CD4+ T cells cover dozens of epitopes across the spike proteins used for the vaccines. The immune system is fuzzy enough to deal with mutations. It wouldn't be very good if it didn't. Could full escape happen? Sure. Is it likely? Not really.https://www.biorxiv.org/content/10.1101/2021.02.27.433180v1 …
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