you mean that growing corn, a grass, on the great plains, which supported grass for 10,000 years is unnatural Rob?

Fertilizer rates are pretty low; 70 lbs per acres is common. It's often a bit tricky to get the cone spreader adjusted to dispense that little. Anyway, all hail the Haber-Bosch Process.
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If you do it all at once, yes, but most folks I know split up their applications ¯\_(ツ)_/¯
End of conversation
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