Just to give you a concrete example of how this isn’t just stupid pessimism: Think about how many times you’ve gotten a cold. 25% of the time it was the coronavirus. And there are studies that the same one (there are a bunch) can make you sick over and over.
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In 10 years, the idea that you just got “the ‘rona” and you were debilitated for 2 weeks could just be a widely accepted social phenomenon.
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Some reasons I could be wrong: - more money and brainpower are being poured into this than any other disease in history - rats and whales are both mammals, coronaviruses can be different - even if no vaccine we may find some treatments that reduce the chance is death or damage.
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Credible reinfection report? All I’ve seen were either questionable or later debunked.
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I saw a convincing case recently that occurred several months later, but I do not know whether the person in question had any immunological impairments. Prior to that, I had not seen any plausible examples at all. I think it is still very rare.
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What about an effective vaccine but only good for 6 months?
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Good point. I didn’t consider that.
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I disagree. T-cell response is often more important than serum neutralizing antibody titre in adaptive immunity. The failure of earlier CoV vaccines was largely mediated by inappropriate adjuvant selection prompting Th2 response. Current candidates do not have this issue.
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What adjuvants are at the top of the list for covid vaccine?
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We don't know that covid antibody response is temporary
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Other coronavirus like cold and flu have temporary immunity because of quickly mutating virus. Same with covid.
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