No wonder animal models fail to translate so often > “safe and well-tolerated” in an academic animal study means the animals didn’t look sick nor did they die. But it doesn’t mean that even gross organ pathology was ruled out
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It would be interesting to look at historical trends. My impression is that science was always flawed this way but was self-correcting so not a problem. But it is a lot worse under neoliberal university policies of last few decades.
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