i am confused as to why remdesivir would specifically target viral genome replication if it's just an adenosine analogue
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so the explanation is "it just happens to have exactly the right shape idk"- there's biology for you
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I don’t think so, although maybe I’m missing something? If you hang random junk off a nucleoside, it’s pretty likely to screw up the polymerase.
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But, broadly speaking, same principle as the nucleoside anti-HIV drugs, I take it? Screw up viral nucleic acid synthesis more than human’s
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