Wondering how fast remdesivir production can be ramped up if bureaucratic obstacles are removed.https://twitter.com/Chenbariatrics1/status/1238328364911345665 …
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The synthesis shown in the wiki article doesn’t look scalable (but finding better routes might be straightforward, I have no idea, I’m not a chemist) https://en.wikipedia.org/wiki/Remdesivir
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I hope every medicinal and process chemist is putting any spare time thinking into how to make remdesivir in bulk.
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Ah! This is encouraging: looks like the bulk synthesis pathway has been worked out. h/t @ajkirby01 https://www.who.int/ebola/drc-2018/summaries-of-evidence-experimental-therapeutics.pdf?ua=1 …pic.twitter.com/8puATBXKvd
3:47 PM - 13 Mar 2020
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