I read the claim recently that compounds used recreationally are unusually likely to have therapeutic effects compared to random chemical
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it seems uncontroversial but I can’t find the source or any attempt at quantifying - anyone remember what I’m talking about?
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they’re including drugs used by human communities throughout the world including psychedelics not just what we’d call “recreational”
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I’m never gonna find it again huh
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omg
@TristanSevers found it http://slatestarcodex.com/2017/06/05/is-pharma-research-worse-than-chance/ …pic.twitter.com/9BaDOeQTyz
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I think the actual explanation is something like this: 1. Druggies are trying to feel good specifically (positive affect, interestingness)
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2. Pharma is trying to “treat constructs” but what consumers actually care about is feeling good and nothing else matters much
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Mental illness constructs aren’t actually what people (consumers/patients) care about, they care about feeling shitty or not
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Since DSM tends to have “clinically significant distress” thresholds for disorders you should be able to knock them all out by fixing that
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Replying to @literalbanana
Pharma is specifically looking for things that are not too much fun, because that would be immoral, or lead to abuse, or lead to you telling your boss to fuck off, or whatever. Nothing too dramatic please.
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Yes, from having worked in the industry, including on psych drugs, I can say “might make you feel good” is fatal to potential pharmaceuticals. Along with, e.g., “effective aphrodisiac”
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