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MarkHoofnagle's profile
Mark Hoofnagle
Mark Hoofnagle
Mark Hoofnagle
@MarkHoofnagle

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Mark Hoofnagle

@MarkHoofnagle

Trauma/Critical Care/Acute Care Surgeon. MD/PhD. FACS. UVa/UMD/UPenn. Asst Professor of Surgery at Wash U. Blocking is curating.

St Louis, MO
surgery.wustl.edu/people/mark-ho…
Joined March 2012

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    1. Mark Hoofnagle‏ @MarkHoofnagle 6 Apr 2020

      Mark Hoofnagle Retweeted Carlos del Rio

      A small study, but done carefully, with completely the opposite result of the (also small) study by the guy who acts like a grifter. Hmmm. Think this “nonspecific antiviral” effect of HCQ and AZ looking like magic beans.https://twitter.com/CarlosdelRio7/status/1246949861624250369 …

      Mark Hoofnagle added,

      Carlos del RioVerified account @CarlosdelRio7
      No Evidence of Rapid Antiviral Clearance or Clinical Benefit with the Combination of Hydroxychloroquine and Azithromycin in Patients with Severe #COVID19 Always good to read something written by the outstanding ⁦@jmmolinaparis⁩ this is a “must read”. https://www.sciencedirect.com/science/article/pii/S0399077X20300858 …
      1 reply 9 retweets 42 likes
      Show this thread
    2. Mark Hoofnagle‏ @MarkHoofnagle 6 Apr 2020

      But it does speak to an interesting phenomenon - that of physicians who seem willing to sacrifice credibility to get public attention for sloppy work. The behavior is quite cranky, and I’m sure the defense against negative studies will be claims of persecution and conspiracy.

      1 reply 2 retweets 27 likes
      Show this thread
      Mark Hoofnagle‏ @MarkHoofnagle 6 Apr 2020

      The usual, and inevitable progression will be (same as vit C bugs) that the “miraculous” therapy: 1. Only works if given early (the missed window excuse) 2. Only works in ‘x’ clinical subset 3. Only works with higher dose (when a little fails, give more!) ...

      9:40 AM - 6 Apr 2020
      • 18 Retweets
      • 53 Likes
      • Kate Renzenbrink 💙 CNMIO Rick F. Constantinos Kyriakis Scott Bolton, MD Atomsk's Sanakan JD Daniel Tillett Michael Brown Kyle Sheldrick
      4 replies 18 retweets 53 likes
        1. New conversation
        2. Mark Hoofnagle‏ @MarkHoofnagle 6 Apr 2020

          4. Is immune to study by academics because they’re owned by pharma and there is no money to be made on generic 5. 6. Doesn’t work to treat severe disease but merely progression of the disease (modified missed window) ...

          1 reply 4 retweets 34 likes
          Show this thread
        3. Mark Hoofnagle‏ @MarkHoofnagle 6 Apr 2020

          6. Can’t be studied further and pound the table, yell efficacy is established and it’s a crime not to give it a try because it might save some lives we just don’t know which ones. 7. You would want it to be used on *your* loved one if your choice at a chance to save their life.

          1 reply 3 retweets 30 likes
          Show this thread
        4. Mark Hoofnagle‏ @MarkHoofnagle 6 Apr 2020

          Basically, endless excuses followed by yelling and then emotional blackmail. You know, like how scientists do. 🙄

          3 replies 3 retweets 36 likes
          Show this thread
        5. End of conversation
        1. Kevin Kehres‏ @kevin_kehres 22 Apr 2020
          Replying to @MarkHoofnagle

          3a. The dose was too high. I've seen that excuse as well.

          0 replies 1 retweet 6 likes
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        1. RCP‏ @RCPrentice 22 Apr 2020
          Replying to @MarkHoofnagle

          Only works if given with X. If that fails, it only works given with X AND Y.

          0 replies 1 retweet 7 likes
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