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Prikvačeni tweet
Read the January issue! http://bit.ly/2QUMNdI pic.twitter.com/iGthB7aNrb
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Lysine Specific Demethylase 1 (LSD1) promotes epithelial-mesenchymal transition via AKT in
#ColorectalCancer with a mutation in the catalytic subunit of#PI3K. Paper by Miller et al@GCDB_IU@IUMedSchool http://bit.ly/2SdOxy6 pic.twitter.com/PUAsDiOX6B
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Read the February issue! http://bit.ly/3b2lVjX pic.twitter.com/9Sc4NAbrJ2
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Liu et al find Ubiquitin-conjugating enzyme E2C (UBE2C) elevated in patients with
#EndometrialCancer and upregulation to be associated with patient poor outcome. Read more about the molecular mechanisms involved here: http://bit.ly/398fXMH pic.twitter.com/8lDzuru8X3
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Molecular Cancer Research proslijedio/la je Tweet
Check out
our new combo targeting #epigenetic regulator G9a and Chk1 to cause replication
catastrophe in #PancreaticCancer!!! in @MCR_AACR @LomberkLabhttps://mcr.aacrjournals.org/content/early/2020/01/28/1541-7786.MCR-19-0490 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Combined inhibition of Src and
#EGFR improves overall survival in mouse model of#PancreaticCancer by targeting#STAT3 signaling and remodelling#TumorStroma, Dosch et al report.@umiamimedicine http://bit.ly/2tWuVq9 pic.twitter.com/bFebOKtdJ5
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Stangl et al show that all
#BRAF fusions convey resistance to targeted#monotherapy against the#EGF receptor family but fusion partners influence the#oncogenic effects.@UMCUtrecht http://bit.ly/2GIZphU pic.twitter.com/27EQfBrdLJ
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Targeting
#HSF1 has significant therapeutic effects: it reduces#TumorBurden and sensitizes malignant cell death in T cell#AcuteLeukemia cell lines Eroglu et al. report here: http://bit.ly/2RAoPVg@MCG_AUGpic.twitter.com/jlOLzn39D4
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#CentrosomeAmplification (CA) in cancer disrupts#autophagy and sensitizes cells to autophagy inhibition. Denu et al suggest CA as#PredictiveBiomarker for treatment with autophagy inhibitors.@RyanDenu@uwsmph@UWCarbone http://bit.ly/2GxMJua pic.twitter.com/yoM3ULOWBB
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Molecular Cancer Research proslijedio/la je Tweet
Proud to share our recent study
@MCR_AACR: O-GlcNAc transferase regulates cancer stem-like potential of breast cancer cells https://mcr.aacrjournals.org/content/early/2020/01/23/1541-7786.MCR-19-0732 … Congrats to first author Neha@neha_manjari and co-authors Giang, Lorela@loriciraku, Ayonika, Zach, Dimpi and Val!Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Can colorectal
#CancerCells be reverted into normal-like cells? Lee et al find that depletion of histone methyltransferase#SETDB1 reactivates colon-specific genes and supresses#StemCell associated genes.#KAIST http://bit.ly/2GmsaAO pic.twitter.com/k6u8a7Q3XH
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Molecular Cancer Research proslijedio/la je Tweet
Antibody–Drug Conjugates: A Comprehensive Review (27 pages of references) Selection of antibody moiety, Linkers, Cytotoxic payloads or warheads, MoA of ADCs, Resistance, Optimization strategies, ADCs in clinical dev, Conclusions & perspectives https://mcr.aacrjournals.org/content/18/1/3 pic.twitter.com/Od8uI3AFgR
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Molecular Cancer Research proslijedio/la je Tweet
Excited to share my manuscript reporting the dependency of breast cancer stem-like cell characteristics on OGT (an intracellular sugar post-trans mod) and proteins that may facilitate this.
@MCR_AACR thank you to my colleagues and advisor@LabReginatohttps://mcr.aacrjournals.org/content/early/2020/01/23/1541-7786.MCR-19-0732 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
PRMT6/ILF2/MIF signaling axis plays a unique role in promoting
#LungCancer. Avasarala et al discuss new therapeutic opportunities by developing inhibitors of#PRMT6 and ILF2 heterodimerization.@UIHealth@UICancerCenter http://bit.ly/2TM8puy pic.twitter.com/DQrZ37goGm
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Nguyen et al propose higher reactive oxygen species levels plus increased KYN/TRP ratio as relevant biomarker to select
#LungCancer patients for future treatment with#IDO1 inhibitors@DeptVetAffairs@UMiamiHealth http://bit.ly/2tHt0We pic.twitter.com/yBGiMO6orY
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Zhang et al show that deregulated RNA binding protein Argonaute 2 acts as a MYC transcript stabilizer to promote hepatocellular carcinomas independent of miRNAs.
@JEFFsurgery http://bit.ly/2NP7p50 pic.twitter.com/hoZb4vZMmg
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Combined inhibition of Src and
#EGFR improves overall survival in mouse model of#PancreaticCancer by targeting#STAT3 signaling and remodelling#TumorStroma, Dosch et al report@umiamimedicine. http://bit.ly/2tFdbiD pic.twitter.com/yk2FfcJ7NN
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Molecular Cancer Research proslijedio/la je Tweet
Interesting new work in HCC with contribution from two
@NCI_SurgOncFel@DDominguezMD and@SeanMartinDO in Xin Wei Wang’s lab in the Laboratory of Human Carcinogenesis at the@theNCI@NCIResearchCtr@MCR_AACRhttps://twitter.com/DDominguezMD/status/1217816917584510977 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Molecular Cancer Research proslijedio/la je Tweet
My first paper in grad school! We report a dependency of some highly aggressive, metastatic breast cancer cells on mitochondrial serine and one-carbon unit metabolism. Available online at
@MCR_AACRhttps://mcr.aacrjournals.org/content/early/2020/01/15/1541-7786.MCR-19-0606 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Targeting
#HSF1 has significant therapeutic effects: it reduces#TumorBurden and sensitizes malignant cell death in T cell#AcuteLeukemia cell lines Eroglu et al. report here: http://bit.ly/2FNBYn7@MCG_AUGpic.twitter.com/StRF9OsgOE
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