Lisa Gralinski

@LisaGralinski

Coronavirus pathogenesis, UNC basketball, good food, adventure travel

University of North Carolina
Vrijeme pridruživanja: veljača 2013.
2 fotografije ili videozapisa Fotografije i videozapisi

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  1. prije 16 sati

    5) The number of tests being performed each day in China is truly impressive. How long can this pace (and supply) keep up?

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  2. prije 16 sati

    4) Controlling this outbreak will require the time/resources to monitor and test close contacts of known cases, not just identify those with severe disease. This seems a long ways off in China but has been pretty successful so far in other countries.

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  3. prije 16 sati

    ...Once testing is rapid after symptom onset, to allow early isolation/treatment of positive cases, the hope is that new cases numbers will start to drop.

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  4. prije 16 sati

    3) Widespread community spread will continue if hard hit areas are still full of patients trying to be seen by a doctor (as currently seems to be the case)...

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  5. prije 16 sati

    2) Would love to see more about the date of symptom onset vs. the date of positive test to get a sense of how close/far the hard hit areas are from getting on top of the case load. The system is probably too overloaded for this type of tracking right now though.

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  6. prije 16 sati

    Thoughts on today’s numbers: 1) Another huge increase in China with 3887 new cases, still led by Wuhan and Hubei Province. Even with the new hospital space that’s an overwhelming burden for one city to manage

    12 proslijeđenih tweetova 22 korisnika označavaju da im se sviđa
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  7. 3. velj

    Important update on human to human transmission here, the most widely noted case of asymptomatic transmission actually did have some symptoms. This is good news for disease control and I’m glad the record will be corrected!

    That paper claiming that an asymptomatic traveler from Shangai infected a business partner in Germany with the new coronavirus was wong! The woman did actually have symptoms, found out.
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  8. proslijedio/la je Tweet
    3. velj

    The identification and characterization of a novel coronavirus associated with the recent outbreak of respiratory illness in China reveals similarities with SARS coronaviruses, according to a study published in Nature.

    5 replies 111 proslijeđenih tweetova 136 korisnika označava da im se sviđa
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  9. proslijedio/la je Tweet
    2. velj

    If you want to hear more abt this paper, which suggested that what we know now as could become reality, and talked to abt it on in 2015. It’s ironically titled ‘It’s not 2.0”.

    2015 paper showing how a Chinese bat recombined with a SARS-CoV can use ACE2 to efficiently enter human airway cells and replicate, suggesting “a potential risk of SARS-CoV re-emergence from viruses currently circulating in bat populations.”
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  10. 2. velj

    Another huge increase from China tonight (2590 new cases, 45 deaths). Even with new hospitals going up, it's an overwhelming number of patients to treat. Severe disease seems to develop late in infection so the bed space (ICU space?) problem is only going to get worse.

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  11. 31. sij

    Two thoughts on this case report 1) so much credit to the patient for being aware and taking appropriate action after developing symptoms and 2) props to for leading the mouse studies that showed remdesivir is efficacious against many coronaviruses!

    First US patient treated with . Hard to wrap your mind around the fact that your pipetting may have helped save a human life
    10 proslijeđenih tweetova 33 korisnika označavaju da im se sviđa
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  12. 30. sij

    Great points here. We’re much better at reacting to emergencies than maintaining global screening and prevention efforts.

    But, experience says history will repeat itself. and when the panic is over, no one will want to invest in preparedness and prevention. I am either getting cynical or realistic. The next pandemic is coming. We’re not prepared for it.
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  13. 30. sij

    So, so fast. Glad the world is aware and sharing so much information this time.

    surpassing (8,253) the case count (8,098) in a month
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  14. 30. sij

    So much this. 1. Masks don’t help the way most people think they do. 2. There is no need for home PPE right now. 3. Don’t waste supplies that medical providers and scientists might actually need. 4. Fearmongering - don’t do it.

    I have a few issues with this tweet, the first of which is why are we fearmongering AGAIN, the second is that N95s have to be FIT TESTED. If you haven’t had a professional do a fit test, they’re not efficacious. If you have facial hair, they are not efficacious.
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  15. 30. sij

    Bad news, glad this case has been discovered now so that contact tracing can start. I can understand the fear but effective public health measures rely on a collective sense of responsibility. (Plus doctors can do their best work when they have all of the facts!)

    a local news reporting a patient hid his travel history in china and stayed in general ward and turns out he is a positive... That could be disastrous superspreading nosocomial event...
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    30. sij

    Latest figures.

    15 replies 102 proslijeđena tweeta 139 korisnika označava da im se sviđa
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  17. proslijedio/la je Tweet
    30. sij

    Perlman and Denison discuss the potential for nCoV to mutate and why it may or may not have an effect viral spread and disease potential

    1 reply 17 proslijeđenih tweetova 34 korisnika označavaju da im se sviđa
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  18. 30. sij

    Massive amounts of work being done in screening laboratories and hospitals, the world needs to recognize this effort.

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  19. 30. sij

    No decrease in new cases today, but it does seem like China is doing a great job in identifying and testing.

    1. China's new numbers are up. For Jan. 29. New cases: 1737 Total cases: 7711 New deaths: 38 Total deaths: 170 Tibet confirmed its first case. (The X is through a number that's clearly a typo.)
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  20. proslijedio/la je Tweet
    29. sij

    Due to the emergence of 2019-nCoV and the rapid response by the coronavirus community, ASV will have a workshop dedicated to 2019-nCoV research. Abstracts will be accepted for this topic Feb 10 - May 1.

    1 reply 57 proslijeđenih tweetova 90 korisnika označava da im se sviđa
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