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Prikvačeni tweet
3/3 On the single cell level, only male, but not female, mice had increased number of disease associated microglia (DAMs) and decreased homeostatic microglia after microRNA removal in tauopathy mice. https://www.nature.com/articles/s41593-019-0560-7 ….
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Gan Lab proslijedio/la je Tweet
Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophyhttps://www.nature.com/articles/s41586-020-1984-7 …
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Gan Lab proslijedio/la je Tweet
Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains, exciting work by
@FitzpatrickLab et al.!https://www.cell.com/cell/fulltext/S0092-8674(20)30108-2?rss=yes …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
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Microglia make you forget. Microglia mediate forgetting via complement-dependent synaptic eliminationhttps://science.sciencemag.org/content/367/6478/688 …
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Please join us next Wednesday, February 12th at the Appel Institute Forum on Neurodegeneration featuring Debra Abramov, a Graduate Student from the lab of Dr. Jacqueline Burré.pic.twitter.com/6eSjk2VbZT
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A study using iPSC from Yong-Onset Parkinson's Disease patient showed increased accumulation of soluble α-synuclein protein and reduced abundance of LAMP1, which can be normalized by specific phorbol esters, the activator of lysosome.https://www.nature.com/articles/s41591-019-0739-1 …
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A transcriptomic study of individual primary human cortical cells from different developmental periods and cortical areas provides datasets and analytical tools for evaluating cortical organoids as models of human brain development.https://www.nature.com/articles/s41586-020-1962-0 …
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Gan Lab proslijedio/la je Tweet
Interesting paper on insulin & BBB in mice: males v females and E3 v E4. Results: 1) females greater serum clearance of insulin 2) differences in insulin at BBB due to apoE&sex, E4 more ins binding to brain vasculature, 3) ins uptake in hippocampus not detected in several groups.https://twitter.com/HartmanNeuroLab/status/1224179455557431297 …
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Gan Lab proslijedio/la je Tweet
Exome-wide age-of-onset analysis reveals exonic variants in ERN1, TACR3 and SPPL2C associated with Alzheimer's diseasehttps://www.biorxiv.org/content/10.1101/2020.01.28.923789v1 …
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Please join us this Wednesday, January 29th at the Appel Institute Faculty Candidate Seminar
@WeillCornell featuring Or Shemesh, a Postdoctoral Fellow in Synthetic Neurobiology at the Massachusetts Institute of Technology.pic.twitter.com/MDvEQFCi97
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A nice review from Tsai group/MIT about using current iPSC technologies to study neurodegenerative disorders such as Alzheimers' disease, including challenges and future directions.https://www.nature.com/articles/s41380-019-0468-3#article-info …
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Gan Lab proslijedio/la je Tweet
Another great story by
@wysscoray’s lab. Tony presented this super interesting data at our least year’s meeting in#Tbilisi!https://twitter.com/wysscoray/status/1219426125429915648 …
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Fantastic and well-attended talk today by Dr. Christopher K. Glass at the Tetra-Institutional Alzheimer's Disease Research Seminar Series!pic.twitter.com/0WpUX5YhnQ
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Gan Lab proslijedio/la je Tweet
Join us today for our January Tetra-I AD Research Seminar Series talk, featuring Dr. Christopher Glass from UCSD!
#AlzheimersDisease#microglia
pic.twitter.com/gzcfErMS4y
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Gan Lab proslijedio/la je Tweet
Elevated sTREM2 and inflammation in individuals with Down syndrome. An Altered Relationship between Soluble TREM2 and Inflammatory Markers in Young Adults with Down Syndrome: A Preliminary Reporthttps://www.jimmunol.org/content/early/2020/01/17/jimmunol.1901166 …
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Gan Lab proslijedio/la je Tweet
New study
@NatureComms led by@nfranzme and@MichaelEwers12 suggests that the#functional brain#connectivity is associated with rate of#tau accumulation in#Alzheimer’s disease. https://go.nature.com/38lNceU@biofinder_study@ISD_Researchpic.twitter.com/KWWuOtYOy0
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Please join us next Friday, January 24th at the Appel Institute Faculty Candidate Seminar featuring Joel Blanchard, a Postdoctoral Fellow at the Picower Institute for Learning and Memory at Massachusetts Institute of Technology.pic.twitter.com/26ti85v1b9
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“Like casting a tiny net”, a new technique called “proximity labeling” can capture surface proteins on neurons in the brains. A joined effort from Liqun Luo and Alice Ting groups Identified New cell-surface regulators of brain wiring.https://www.cell.com/cell/pdf/S0092-8674(19)31391-1.pdf …
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Gan Lab proslijedio/la je Tweet
Vascular damage harms the brain and taxes cognition, but not by stoking Aβ deposition, three studies say.
@HopkinsMedicine@lunduniversity#Alzforum http://ow.ly/6oUe50xXBQRHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Ready to explore a different field by
@DanFeldmanPhD, courtesy of Progress in Neuroscience Seminar series@WeillCornell!pic.twitter.com/GU1I2xmfke
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