Léopold Carron

@LeopoldCarron

PhD at : repeat element, chromatin, Hi-C & machine learning. Work with . Active in , Irish folk fan.

Vrijeme pridruživanja: rujan 2015.
Rođen/a 1992.

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  1. 29. sij

    Ma dernière sortie, j'avoue être asse content du résultat! Quelques retours d'expériences pour les doctorants :).

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  2. proslijedio/la je Tweet
    27. sij

    Ci dessous une pétition pour la défense de l'ESR. J'ai signé, et vous ? via

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  3. proslijedio/la je Tweet
    4. ruj 2019.

    ENHANCER SPOOKY ACTION FROM DISTANCE! NO LOOP! NO COLLISION! FAKE NEWS! MECHANISM IS DISTANCE MAKE THE PARP GROW FONDER!

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    8. kol 2019.

    Enhancer features that drive formation of transcriptional condensates [by , , & Co] Combination of TF-DNA & TF-coactivator interactions drives condensates at genomic loci determined by the DNA sequence

    Shrinivas et al. demonstrate that specific types of motif compositions encoded in DNA drive localized formation of transcriptional condensates. These
findings explain how phase separation can occur at specific genomic locations and shed light on why only some genomic loci become highly active enhancers.
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  5. proslijedio/la je Tweet
    7. kol 2019.

    NEW in : A high-resolution 3D genome map of patient-derived glioblastoma stem cells revealing inter-sample heterogeneity and differences in DNA looping and compartmentalization driving cancer-related gene expression.

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    7. kol 2019.
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    12. kol 2019.

    Very proud to present the lab’s first bioRxiv preprint: Great collaboration between and . Main gist is that WAPL is important for maintaining dynamic cohesin to bring promoters and enhancers together. Digest in the thread.

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  8. proslijedio/la je Tweet
    15. kol 2019.

    Chromatin loops associated with active genes and heterochromatin shape rice genome architecture for transcriptional regulation.

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    16. kol 2019.

    Organization of fast and slow chromatin revealed by single-nucleosome dynamics Perturbed nucleosome dynamics by global histone acetylation or cohesin inactivation -> nucleosome-nucleosome interactions organize nucleosomes into fast and slow dynamic domains

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    17. kol 2019.

    Cool new fundamental discovery by on how cells control the activity of genes, through regulation of transcript termination, now in

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  11. proslijedio/la je Tweet
    27. svi 2019.

    Wolf and I reflecting about the roles of joint molecules reversibility during Homologous Recombination in this Current Genetics mini-review!

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  12. proslijedio/la je Tweet
    19. kol 2019.

    Finally our work is published today: We find actively transcribing retrotransposon HERV-Hs form TAD boundaries in primate PSCs.

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    4. lip 2019.

    What are your options for visualizing a network with many attributes? We review the alternatives and introduce a typology in a new state of the art report. w. 1/8

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    5. lip 2019.

    Nice collection of PyTorch (and some TF) Jupyter notebooks for everything deep learning by Sabastian Raschka.

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  15. proslijedio/la je Tweet
    31. svi 2019.

    This review discusses the recent advances in our knowledge of the Polycomb Repressive Complex 2 (PRC2) in mammalian systems.

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  17. proslijedio/la je Tweet
    21. ožu 2019.

    Hey les Geekus biologicus : ça fait 7 ans qu’on peuple les Internets! On est super fiers de vs! On lance 1 petite campagne d’autopromo pr se trouver plein de nvx copains. On a besoin de vs pr ça! l’affiche:

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  18. proslijedio/la je Tweet
    15. svi 2019.

    On pense un peu aux débutants et on vous explique comment récupérer proprement des données de séquençage sur le site du ! Bonne découverte ! cc

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  19. proslijedio/la je Tweet
    5. velj 2019.

    Triplex Domain Finder: A new method to find binding sites between and DNA : Web:

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  20. proslijedio/la je Tweet
    24. sij 2019.

    Nucleosome orientation map finds two new chromatin folding motifs A preview by of the article by Ohno et al. "Sub-nucleosomal genome structure reveals distinct nucleosome folding motifs"

    (A) Hi-CO can identify nucleosome orientations because nucleosome entry and exit points on DNA are marked by adapters so that cleaved and re-ligated DNA fragments can be differentiated from uncleaved DNA fragments. This allows capture of all possible ligation products for a complete survey of nucleosome entry-exit orientations. (B) A tetranucleosome model with stacking of alternating nucleosomes
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