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I'm happy to share this review article I wrote for an upcoming special edition of Human Genetics. The article takes an evolutionary view of GWAS and discusses how selection may contribute to missing heritability (1/n)https://link.springer.com/article/10.1007/s00439-019-02040-6 …
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Lawrence Uricchio proslijedio/la je Tweet
While many of them are quite funny, I'd perhaps stop and think about junior coauthors before posting jokes about retractions. It's quite a stressful situation for them.
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Lawrence Uricchio proslijedio/la je Tweet
Latest paper from our group -- review of new methods for inferring positive selection, led by Hussein Hejase and
@ndukler (sorry, paywall).https://www.cell.com/trends/genetics/fulltext/S0168-9525(19)30269-0 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Lawrence Uricchio proslijedio/la je Tweet
Our latest collaborative publication in
@EvolLetters: thinking on how evolutionary genetics can improve our predictions of species responses to climate change.https://twitter.com/EvolLetters/status/1217542283136000003 …
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Lawrence Uricchio proslijedio/la je Tweet
Proud to share the latest by
@mlspear09! She found a surprising pattern that may have important implications for precision medicine in admixed populations. In Mexican Americans, Native American ancestry increased by ~20% over a 50yr period during the last centry.https://twitter.com/biorxivpreprint/status/1217205817847570439 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Lawrence Uricchio proslijedio/la je Tweet
First preprint during my postdoc is out! With
@emiliahsc@lohmueller and@Bernard_Y_Kim , we asked whether heterosis from recessive deleterious variants can confound adaptive introgression in humans 1/nhttps://twitter.com/biorxivpreprint/status/1217296435340771328 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Lawrence Uricchio proslijedio/la je Tweet
My last dissertation chapter on genetic diversity and divergence in northern Selasphorus hummingbirds is now published in
@journal_evo (!!!)https://onlinelibrary.wiley.com/doi/10.1111/evo.13888 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Lawrence Uricchio proslijedio/la je Tweet
My work with
@Graham_Coop on genetic privacy in genetic genealogy databases that allow uploads is now a paper in@eLife https://elifesciences.org/articles/51810 (1/n)Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Lawrence Uricchio proslijedio/la je Tweet
How much selection is there on synonymous sites? And which processes are responsible? We find that ~15% of synonymous sites in preferred codons are under strong purifying selection. Splicing is the runner up!https://www.genetics.org/content/early/2019/12/23/genetics.119.302542 …
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Lawrence Uricchio proslijedio/la je Tweet
I am very happy that this paper is out. Heroic effort led by
@heatherEmachado and@dlawrie42. https://www.genetics.org/content/early/2019/12/23/genetics.119.302542 … shows that 10-20% of optimal codons within genes are subject to strong selection and some appear to be subject to none. 1/nPrikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Lawrence Uricchio proslijedio/la je Tweet
Suggestions for how to find a putative pseudogene in an unannotated genome?
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Lawrence Uricchio proslijedio/la je Tweet
I’m very excited to share my first preprint as a postdoc with Jeff Jensen and with our coauthor Brian Charlesworth:https://www.biorxiv.org/content/10.1101/2019.12.18.881516v1 …
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Lawrence Uricchio proslijedio/la je Tweet
I am super happy to share our latest foray into the genetic architecture of complex traits! This was a project headed by Kevin-I-can't-believe-you-are-still-not-on-Twitter-Hartman, Sara Rashkin, and
@johnwitte, and was a VERY long time in the making!https://twitter.com/biorxiv_genomic/status/1207693272333856769 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Lawrence Uricchio proslijedio/la je Tweet
In our test for the substantial effect of {population stratification, assortative mating and indirect genetic effects} on UKB GWAS associations, household income almost won the most-clearly-problematic pageantpic.twitter.com/cHxvoMqpX2
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Lawrence Uricchio proslijedio/la je Tweet
New preprint where I simulate background selection matching actual genomic regions' recombination maps and locations of genes/conserved elements, and ask how often the resulting patterns of diversity resemble hitchhiking events (see title for answer):https://www.biorxiv.org/content/10.1101/2019.12.13.876136v1 …
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Lawrence Uricchio proslijedio/la je Tweet
New paper by
@Amber_D_Stubler and myself shows that Unprofessional peer reviews disproportionately harm underrepresented groups in#STEM. Please help us remove the culture of toxic#peerreview. A thread on our key findings: https://doi.org/10.7717/peerj.8247 …@thePeerJ#academicchatterPrikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Lawrence Uricchio proslijedio/la je Tweet
A new tenure-track position in computational genomics at McGill:https://www.genomeweb.com/resources/jobs/assistant-or-associate-professor-tenure-track-computational-genomics?utm_campaign=google_jobs_apply&utm_source=google_jobs_apply&utm_medium=organic …
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Lawrence Uricchio proslijedio/la je Tweet
(Thread) New preprint out. Population genetics of the coral Acropora millepora: Towards a genomic predictor of bleaching. https://www.biorxiv.org/content/10.1101/867754v1 … We are very excited about this work, here a few of the highlights (1/n)
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Lawrence Uricchio proslijedio/la je Tweet
Wow wow wow!!!
@MarjoRousselle &@GaltierNicolas are back with more exciting Ne-DFE stuff!https://twitter.com/biorxivpreprint/status/1203050002978877440 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Lawrence Uricchio proslijedio/la je Tweet
New paper with Stacy Phillpott quantifying the uncertainty/steepness of interspecific dominance hierarchies in tropical arboreal ant communities.https://peerj.com/articles/8124/
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Lawrence Uricchio proslijedio/la je Tweet
Check out my new preprint if you’re interested in inferring parameters of positive selection from the uSFShttps://twitter.com/biorxivpreprint/status/1199384633303015426 …
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