Lauring Lab

@LauringLab

Virologist and Infectious Diseases physician at the University of Michigan. Proud father of 3. Opinions are my own.

Ann Arbor
Vrijeme pridruživanja: kolovoz 2014.

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  1. proslijedio/la je Tweet
    prije 7 sati

    I just sent out a reminder to the lab to encourage them to complete the myIDP survey at . I do this every year at the beginning of February. I encourage them to meet w/ me to discuss to make sure our goals, interests, and needs are aligned

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  2. prije 9 sati

    . Bad headline. As member, I expect better than this. Evidence of RNA in stool is a far cry from infectious virus or transmission. Neither Dr. Lucey nor the NEJM report *suggest* spread of nCoV via fecal-oral route. Case report cautions against this over-interpretation.

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  3. proslijedio/la je Tweet

    Obviously we have all got a bit distracted lately but Virus Genomics and Evolution 2020 (15-17 June) is open for registration:

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  4. 2. velj

    . 12 Groundhog days and going strong!

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  5. proslijedio/la je Tweet
    1. velj

    This paper proposes that there are 4 short "insertions" in the spike protein in copied from HIV. Yesterday, I showed that the proposed inserts are tiny strings that randomly match a whole bunch of things. 2/9

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  6. 1. velj

    *relaying* danger of tweet rants

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  7. 1. velj

    I am happy to be shown where I am wrong here. I encourage all science journalists to ask these sorts of questions or seek out people who know before delaying info like this. I know your job is hard, but we need you to do it well at this time. Done!

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  8. 1. velj

    Ok. What about antibody waning? We’re within 2-3 weeks in most cases. That’s typically time frame to peak IgG titers. Do we really think that this is unlike nearly every other infection and antibodies are already on wane?

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  9. 1. velj

    Sorry at gym with bad internet. More to come.

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  10. 1. velj

    3/ how would detect a superinfection? Diagnostics are based on Nucleic acid detection and would likely recognize all nCoV. People may still have detectable RNA in convalescence. Not nec new infection. Would need fancy sequencing to tell.

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  11. 1. velj

    3/ how would detect a superinfection? Diagnostics are based on Nucleic acid detection and would likely recognize all nCoV. People may still have detectable RNA in convalescence. Not nec new infection. Would need fancy sequencing to tell.

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  12. 1. velj

    2/ strains to my knowledge. Given what we know about diversity of strains in current outbreak and typical rates of evolution, seems unlikely that that has occurred with much frequency.

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  13. 1. velj

    1/ Warning. Pedantic rant. The more I think about this, I doubt there is evidence of superinfection (reinvention with same agent). First of all, this is essentially unheard of. Yes I am aware of HIV etc and antigenic drift in flu. But those examples are with genetically distinct

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  14. 1. velj

    To be clear the article does not talk about any evidence behind this warning. It is similar to a news report earlier in the week warning that pets could get infected with nCoV. Possible yes, but no evidence. This also might refer to higher risk for secondary infections.

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  15. proslijedio/la je Tweet
    31. sij

    Simple & interactive way to explore expected transmissions // mutations under different parameters. this is outstanding 👏👏👏

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  16. proslijedio/la je Tweet
    31. sij

    I've written a blog post on genomic epidemiology and the global scientific response to the outbreak:

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  17. proslijedio/la je Tweet
    31. sij
    Odgovor korisnicima i sljedećem broju korisnika:

    No I don't. does not speak for me, or for or for or for . He has a temporary appointment in our department of nutrition, is not an expert on viruses or evolution, and is seeking publicity not scientific dialogue.

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  18. 31. sij
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  19. 31. sij
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  20. proslijedio/la je Tweet
    Odgovor korisnicima

    You can explore this usine ’s online tool (now handily pre-configured for nCoV):

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