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Millenium, year 1 - $8M in revenue. I think Genentech was in the black <2 yrs from starting. Curious what founding year revenue looks like for the most successful companies in bio.pic.twitter.com/MiOsPnQy0T
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Both life expectancy at birth and at age 65 have increased pretty dramatically since then. Were the causes of death in the population which make up most of the dataset relevant to people today?pic.twitter.com/MTYzoONtGi
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The dataset had many individuals who were born 1900 and earlierpic.twitter.com/GFK7XqPJtf
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Ontogeny recapitulates phylogeny.https://www.youtube.com/watch?v=ub747pprmJ8 …
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Interesting that just crossing in Cas9 appeared to extend lifespan a bit in HGPS mice - might be effect to do w/ other genetic background from that species, curious if mice w/ Cas9 live longer in any other backgrounds? https://www.nature.com/articles/s41591-019-0343-4 …pic.twitter.com/106Yts2cfD
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Confused by the
$TORC data slide - placebo for the 10mg arm is ~27% incidence, but placebo drops to ~20% in 10mg BID arm (same as treated). There's also a 2x difference in RTIs between placebo to 5 mg QD and placebo to 10 mg BID. Does anyone have a best way to interpret?pic.twitter.com/ompFsRgApB
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Also this - never take equity/debt/sell rights/fund your own R&D! Only gifts. Like, I'm not sure I know of anyone who's done that in the most extreme sense, but it's kind of an interesting way to look at the world.pic.twitter.com/gaxrm4frF3
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Often you hear things like the below (Mark Levin w/ funny/surprising comments on Millennium strategy) within a few months of working in industry, but it's really hard to know 'how things work' from the outside.pic.twitter.com/U2Q6QOAjFz
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There's also melodysheep, but the quantum physics videos just repeat basic facts w/o using the music to explore them in any way.https://www.youtube.com/watch?v=uD4izuDMUQA …
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Huh - it's apparently easier to get grants for 'aging' than for any other category funded by NIH (major caveat - that's mostly AD-specific grants, I think). From NIH 2019 budget tables.pic.twitter.com/5Ktpa98i2C
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Is there any good argument for standard deviation over mean absolute deviation (apart from 'it's algebraically simpler' and 'Gaussian something')?pic.twitter.com/M6ZmobIEi7
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Have been trying to think of something to post about this paper so I can mention that it includes owl monkeys. What are owl monkeys you might ask? This - not sure whether cute or an escapee from a furby horror movie. https://www.biorxiv.org/content/10.1101/327627v1 …pic.twitter.com/M4A0nsbtzn
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What are other examples of Moore's law (self-fulfilling prophecies that drove research productivity)?pic.twitter.com/W6RF1NUqUQ
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Curious re 'Are good ideas getting harder to find paper' - are there any individual industries or companies where research productivity went up w/ # of researchers added (overall graph below)?pic.twitter.com/Xn5tCtF5Ik
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Fascinating how much similar animal diversity inspired early flight pioneers - beautiful extract from L'Empire de l'Air.pic.twitter.com/1UU9zdNQYr
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This post-PhD careers article from Berkeley is very (unintentionally?) funny/sadpic.twitter.com/HeyenW9IKe
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Earlier this week: 'We should get some planaria for the office, y'know, just to have them around' Today: 'WOAAHHHHHHHH'pic.twitter.com/brl7HqWHOG
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Delbruck on the impact of WWI 'the worst thing was, they made me joing the Boy Scouts...'pic.twitter.com/T70EhIcTTE
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