Lane Warmbrod

@LaneWarmbrod

Analyst . Biosecurity. Infectious Disease Population Genetics. Biotechnology & Science Policy. Star Wars Nerd. Rocky Top. Thoughts my own

Vrijeme pridruživanja: travanj 2019.

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  1. proslijedio/la je Tweet
    31. sij

    When did last use fed power? Answer: Rarely, even for smallpox, polio, SARS, Ebola, MERS. Andrew Speaker quarantined re MDR TB. Fact is, ph powers reside in states. w/ Ebola, handed cases to states. During 1918 Flu, mass quarantines, but at city level

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  2. 31. sij

    How can we use viral genome data to understand epidemiological patterns and transmission, ultimately to improve response? Check out this tool by

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  3. proslijedio/la je Tweet
    31. sij

    Thanks to rapid and open data sharing by now includes the genome from one of the cases in Bavaria, Germany. It does not seem to group with any other sequences in our phylogeny.

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  4. 31. sij

    The highlight of 2020 (so far) is the series finale of . It was funny, bittersweet, and hopeful. Just what I needed to distract from the outbreak and politics.

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  5. proslijedio/la je Tweet
    29. sij

    More viral genomes have been sequenced from around the world & placed in phylogenetic context by & team. I’ve copied a screenshot below that shows the latest version, plotted in terms of mutational distance from the earliest Wuhan samples. [1/n]

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  6. proslijedio/la je Tweet
    29. sij

    We've been misquoted as concluding #2019-nCoV is recombinant. Just to be clear, there’s no evidence that recombination has anything to do with nCoV's emergence & there's now a non-recombinant bat virus that clusters relatively closely to it see Fig 1B in .

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  7. proslijedio/la je Tweet
    29. sij

    genomes from China are accumulating a bit of genetic diversity (seen at ). This is expected given RNA virus error-prone replication and does not indicate functional differences. 1/3

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  8. 29. sij

    Interested in the outbreak and ? Come hear from the experts!

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  9. proslijedio/la je Tweet
    29. sij

    Quick reminder: Infectivity: ability of agent to enter host and multiply (establish infection) Pathogenicity: ability of agent to cause clinical disease Virulence: degree of severity of the disease It may seem trivial, but the differences are important!

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  10. proslijedio/la je Tweet
    28. sij

    Each day we learn more about the outbreak. Here is a on 5 key questions and terminology in infectious disease epidemiology to help make sense of all of this information.

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  11. proslijedio/la je Tweet

    for 1 month: Towards a comprehensive catalogue of validated and target-linked human enhancers by , Jacob Tome &

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  12. 28. sij

    Want an overview of the genomics of that summarizes the incredible work of of virologists and geneticists around the world? Check it out here!

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  13. proslijedio/la je Tweet
    28. sij

    Seasonal CoV & SARS CoV Live Full-Genome Builds

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  14. proslijedio/la je Tweet
    28. sij

    Social media companies knew that misinformation during a public health emergency was a threat before , yet this article suggests that these platforms are still playing catch up. We need proactive policies to address this problem.

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  15. proslijedio/la je Tweet
    28. sij

    Thanks to rapid and open data sharing by and through GISAID, we have additional genomes from one case in Taiwan and two cases in California. Latest data and analysis is up at . 1/4

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  16. proslijedio/la je Tweet
    28. sij

    This strain and the outbreak clade are separated from their common ancestor by ~0.02 substitutions per site. Assuming a coronavirus evolutionary rate of between 3 and 8 x 10^-4 subs per site per year, we estimate roughly 25 to 65 years from a common ancestor. 2/2

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  17. proslijedio/la je Tweet
    27. sij

    I know its busy in China, but no new sequences in the last five days from the mainland. Some officials have mentioned the virus is adapting. Is that conjecture, or is there sequence data to support? Will be waiting & looking forward to and analysis of seq

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  18. proslijedio/la je Tweet

    There are now 110 people across 26 states being monitored for potential infection. With the number of confirmed US cases totaling 5, reports no new confirmed cases since last night.

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  19. proslijedio/la je Tweet
    27. sij
    Odgovor korisnicima i sljedećem broju korisnika:

    More people should watch "Clade X" the tabletop pandemic exercise to understand preparedness, and why travel bans and quarantines rarely work.

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  20. proslijedio/la je Tweet
    26. sij

    "Patient 5 was later confirmed virologically to have an asymptomatic infection." From What is the proportion of infected asymptomatic or subclinical people who are transmitting the infection? This may facilitate the epidemic.

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