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Hypothesis: one reason that the anti-vax viewpoint is so popular is because injections are a viscerally terrifying thing. People have fears/phobias about injections, and those fears provide a really strong prior of "actually this thing is bad".
It would be like if you could prevent heart attacks by letting a special medical spider bite you once a year. The spider is gigantic and has yellow and black stripes, and you get a big sore welt around the bite every year. But hey, the doctors know best.
(To be clear I think vaccines are great. Just trying to understand why anti-vaxxing is a popular viewpoint.)
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