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An exclusive interview with our
@JohannaSyrjanen on her CALHM story. She describes CALHM1 and CALHM2 as#odd_holes CALHM was originally discovered by Philippe Marambaud@FeinsteinIMR here on Long Island, NY.https://www.cshl.edu/new-look-at-odd-holes-involved-in-taste-alzheimers-asthma/ …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Hiro Furukawa Lab proslijedio/la je Tweet
Hereby the
#SharedIt link to the NSMB article https://rdcu.be/b0UOp 'Structure and assembly of calcium homeostasis modulator proteins' by Hiro Furukawa & colleagues. If interested, take a look also at the related study out in@nature https://www.nature.com/articles/s41586-019-1781-3 ….https://twitter.com/PDBeurope/status/1222429721071378432 …
0:12Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Hiro Furukawa Lab proslijedio/la je Tweet
There are 214 new entries in the PDB this week, including this
#cryoem structure of CALHM2 (6vai), published@natureSMB. Find all the latest entries at http://PDBe.org/latest pic.twitter.com/TUx7850ofBHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Hiro Furukawa Lab proslijedio/la je Tweet
Exciting new collaborative paper from David Jane’s lab
@BristolUni on NMDA receptor subunit specific antagonists in Nature Comms (https://www.nature.com/articles/s41467-020-14321-0 …) with accompanying discussion here (https://bioengineer.org/new-tool-for-investigating-brain-cells-parkinsons-and-more/ …) including a cool YouTube video from collaborating@Lab_FURUKAWAHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
It was fun to work with true scientists from the groups of
#Niko_Grigorieff and@ProfKalium The core of the current work was posted on@biorxivpreprint last year. https://www.biorxiv.org/content/10.1101/857698v1 … We will submit the raw images, soon.Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Our work on CALHM1 and 2 is now officially out
@NatureSMB Voltage sensitive CALHM1 is 8-meric whereas insensitive CALHM2 is 11-meric. Substituting the cytoplasmic domain of CALHM1 with that of CALHM2 converts CALHM1 to an 11-meric channel. 1/2)https://www.nature.com/articles/s41594-019-0369-9 …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Hiro Furukawa Lab proslijedio/la je Tweet
Structural basis of subtype-selective competitive antagonism for GluN2C/2D-containing NMDA receptors
@Lab_FURUKAWA https://go.nature.com/2RD3zgo pic.twitter.com/lnXccX5bYJ
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Our quest for 2C/2D subtype targeting of NMDARs by a great collaboration with the group of
#David_Jane@BristolUni and others. xray xtallography on a fragment of NMDARs, and electrophysiology to define subtype-selective elements. http://disq.us/t/3li08ve pic.twitter.com/Rf3lIY9rYrOvo je potencijalno osjetljiv multimedijski sadržaj. Saznajte više
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A former member of our lab,
#Erkan_Karakas published his first paper as an independent investigator@VanderbiltU A beautiful structure and an intriguing insight into an auto-inhibitory mechanism of IP3Rs! We are all very proud of him! http://www.jbc.org/cgi/content/long/RA119.011570v1 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
A fun collaboration with
#Toshi_Kawate_lab@Cornell. Our pannexin channel structure by#cryoEM is out on@biorxivpreprint. Panx1 forms a 7-mer channel with a narrow extracellular gate involved in channel regulation and ion selectivity. Happy 'Hole'-idays.https://twitter.com/biorxivpreprint/status/1211702588267102208 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Another PHD is made! Jue (Dr. Wang)
@juexiangwang@wsbsbot will be consulting@BCG starting from January 2020. We’ll miss her a lot but are excited to see her take the next career step. Best of luck with your next endeavor Jue!pic.twitter.com/oUGTYDFIC9Ovo je potencijalno osjetljiv multimedijski sadržaj. Saznajte više
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Our work on CALHM1 and 2 structures is now out on
@biorxivpreprint These two CALHM channels have distinct oligomeric states (8-mer and 11-mer). A great collaboration with@ProfKalium and#NikoGrigorieff#cisTEM#WARP@DTegunovhttps://twitter.com/biorxivpreprint/status/1199802904279994368 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Hiro Furukawa Lab proslijedio/la je Tweet
The Smith Lab has an opening for an NIH-funded postdoctoral position in membrane transport! Candidates trained in chemistry, biochemistry, biophysics or related fields are welcome to apply. Please RT widely! https://sites.google.com/a/umbc.edu/smithlab/ …
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What a beautiful and heartwarming way to use a 3D printer! Thanks Andrew
@AndrewPlested for sharing this with us. Be careful not to drop it. You can easily break (deglycosylate) the N-linked sugar chains.https://twitter.com/AndrewPlested/status/1191665401312301057 …
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She nailed it! Jue
@juexiangwang successfully defended her thesis. Many thanks to the thesis committee members@leemorj@megeblad#LindaVanAelst and#BoLi and our external examiner#CrinaNimigean@WeillCornellpic.twitter.com/mC5gnb3AR8Ovo je potencijalno osjetljiv multimedijski sadržaj. Saznajte više
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Hiro Furukawa Lab proslijedio/la je Tweet
The structural mechanism of TRP channel temperature gating is uncovered and critically involves membrane lipids. We propose that the temperature sensor is the transmembrane domain. Details@ https://www.nature.com/articles/s41594-019-0318-7 … https://sobolevskylab.org/structural-basis-of-temperature-sensation-by-the-trp-channel-trpv3/ … https://www.cuimc.columbia.edu/news/images-offer-most-detailed-glimpse-yet-how-skin-senses-temperature …
@AppuKum74640209pic.twitter.com/Y5YnkDhRzv
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Join us! We now have two new postdoc positions available in our group to conduct studies on receptor/ion channel/membrane protein structure, function, engineering, and reagent development by a multidisciplinary approach
@CSHL https://biophysics-jobs.careerwebsite.com/job/postdoctoral-fellowships-in-structural-neurophysiology-at-cshl/51043395/ …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Hiro Furukawa Lab proslijedio/la je Tweet
Excited to announce you can now submit directly from bioRxiv to journals that use the ScholarOne submission system - first up is Royal Society’s Open Biology - hopefully many more to come :-)
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Hiro Furukawa Lab proslijedio/la je Tweet
Spatial coupling tunes NMDA receptor responses via Ca2+ diffusionhttps://www.jneurosci.org/content/early/2019/09/11/JNEUROSCI.0901-19.2019 …
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Hiro Furukawa Lab proslijedio/la je Tweet
Structure of a temperature-sensitive TRP channel TRP1 from the alga Chlamydomonas reinhardtii that has a unique architecture and 2-fold symmetry. Details @ https://rdcu.be/bQ07J https://sobolevskylab.org/structure-of-the-thermo-sensitive-trp-channel-trp1-from-the-alga-chlamydomonas-reinhardtii/ … https://www.nature.com/articles/s41467-019-12121-9 …
#CryoEMpic.twitter.com/m4AJIVXJAs
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