“Polygenic scores are not pure measures of ‘inborn ability,’ and genome-wide association studies of human intelligence and educational attainment are not inevitably ushering in a new eugenics age.”https://leapsmag.com/genetic-test-scores-predicting-intelligence-are-not-the-new-eugenics/ …
-
Rare variants can certainly be captured in principle by whole genomes. But can they be identified as affecting a trait if they are exceedingly rare and the effect is relatively small? That sounds like a hard statistical problem, even with huge datasets.
Depends on their effect sizes and frequencies. Perhaps you can find a sweet spot where we can't reasonably find them, e.g. with small effect sizes (e.g. 0.01 IQ) and frequencies below 1 in 1e-6. Progress is made fast, so I don't expect us to end up in that situation.
Loading seems to be taking a while.
Twitter may be over capacity or experiencing a momentary hiccup. Try again or visit Twitter Status for more information.