Note how casually the authors noted the evidence they found of between group heritability for disease risk.pic.twitter.com/CFXUulcZlI
You should use mixed samples to train polygenic models for mixed groups. Fear of hidden population strat misplaced. http://www.biorxiv.org/content/early/2017/02/01/051458 …pic.twitter.com/naPSa5XvRf
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and again. Seems ok to talk about how unlucky Amerindians are with T2D genetic risk. Next step: educational attainment.pic.twitter.com/9PIogXpo0z
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lol, people are still denying there are genetic differences in height..... it'll be awhile even once the molecular genetics data can show it
End of conversation
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Kinda need the mixed training samples in the first place though...
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As you can see, even samples of unequal sample size can have rather large positive effects on validity of the model.
End of conversation
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