Africa may be genetically diverse, but that doesn't mean what you think. Genetic diversity ≠ phenotypic diversity.https://twitter.com/gcochran99/status/876120409401417730 …
-
-
Replying to @JayMan471
This strange argument seems to have become quite fashionable as of lately.
1 reply 0 retweets 1 like -
-
Replying to @jonatanpallesen @JayMan471
Founder effects are well known. They reduce genetic diversity but generally don't affect polygenic traits.
1 reply 0 retweets 1 like -
Replying to @KirkegaardEmil @JayMan471
Why wouldn't they affect polygenic traits
1 reply 0 retweets 0 likes -
Replying to @jonatanpallesen @JayMan471
Affected loci are randomly distributed hence no impact on polygenic traits, but possibly large on monogenic.
1 reply 0 retweets 1 like -
Replying to @KirkegaardEmil @JayMan471
It depends on the size of the founder sample, if it's smaller the variation can be important. Plus the subset may not be random.
1 reply 0 retweets 1 like
Replying to @jonatanpallesen @JayMan471
Also depends on number of causal variants. The larger, the smaller effect. Nut do some simulations!
10:10 AM - 18 Jun 2017
0 replies
0 retweets
0 likes
Loading seems to be taking a while.
Twitter may be over capacity or experiencing a momentary hiccup. Try again or visit Twitter Status for more information.