Reanalysis takes apart ENIGMA #ADHD study @TheLancetPsych. Would love to hear your thoughts (ping @Neuro_Skeptic).
https://www.madinamerica.com/2017/04/lancet-psychiatry-needs-to-retract-the-adhd-enigma-study/?utm_content=buffer4467d&utm_medium=social&utm_source=twitter.com&utm_campaign=buffer …
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I took a look at the supplementary material and IQ diff is troubling for the paper's message - IQ consistently higher in ADHD than Controls
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Replying to @ar0mcintosh @EikoFried and
This makes the finding stronger, not weaker. Higher IQ -> larger brain, so smaller ADHD vs. no-ADHD gap. (But sure, weak study.)
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Replying to @KirkegaardEmil @ar0mcintosh and
Is hippocampal volume related to intelligence?
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Replying to @EikoFried @KirkegaardEmil and
Also, not controlling for a covariate on which groups of interest differ makes a statistical analyses stronger?
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Replying to @EikoFried @ar0mcintosh and
It does because the direction of the confounder is opposite of claimed effect. And yes, IQ ~~ brain size for ~every area.
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Replying to @KirkegaardEmil @ar0mcintosh and
Update: IQ table was labeled the wrong way (in which case authors should have still controlled for this as covariate that may drive group d)pic.twitter.com/RZSWxQ1HFQ
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Replying to @EikoFried @KirkegaardEmil and
I get the feeling that with the flurry this paper has cause there will be alot of errata coming
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Replying to @ar0mcintosh @EikoFried and
Well, since ADHDers do have lower IQ (about 9 points), this seems fine. http://psycnet.apa.org/journals/neu/18/3/543/ …
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If you control for these things, you change the question from: brain size differences bwtn ADHDers and normies to
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