Near zero validity of polygenic scores in Africans samples. Need more diverse GWAS samples + denser arrays. http://biorxiv.org/content/early/2017/02/05/106062 …pic.twitter.com/YpqGLikxT0
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I would be more persuaded if a trait of comparison had high PGSs in Africans, like type-2 diabetes mellitus.
@KirkegaardEmil
nope. Not the issue. height is fine control trait
Maybe so, but .6 correlation is decent. It's wrong to deny Africans potential benefits, if real. And who else?pic.twitter.com/Hr8usCMFIf
Control for the genomic autocorrelation and see what remains. @UnsilencedSci @hoffsbeefs
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