Non-trivial method variance in polygenic scores calculations. http://biorxiv.org/content/early/2017/02/05/106062 …pic.twitter.com/a5FQRZuJSw
Note: Trivial validity in African sample! Cannot determine causes of group differences with these scores. @KirkegaardEmil
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presumably though it will get better under the "inclusive genomics" trend to make personalized medicine reach all?
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Nature already did a couple calls for more diverse samples in genomics research
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It's due to differential LD with causal variants and the SNPs used as proxies. Will be solved by using larger arrays.
@SilverVVulpes
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