Maybe some of the schizo variations are actually genes that make you smoke cannabis which then causes schizo. @AmirSariaslan
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how do you discriminate from self-medication? see for ex. with tobacco here http://www.ncbi.nlm.nih.gov/pubmed/27164557?dopt=Abstract …
Draw the path model, and find a way to hold the offending path constant. :) @SilverVVulpes @AmirSariaslan
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So, want to hold behav. path constant. One method: see if gen. score predicts schizo among never smokers.
@SilverVVulpes@AmirSariaslanpic.twitter.com/HmCnDJkwNC
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Alternative method: regress schizo on gen. score and cannabis use. See if can. use has incremental validity.
@SilverVVulpes@AmirSariaslan -
First method is better because current gen. scores do not measure gen. risk perfectly.
@SilverVVulpes@AmirSariaslan http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0152719 … - 1 more reply
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