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KirkegaardEmil's profile
Emil O W Kirkegaard
Emil O W Kirkegaard
Emil O W Kirkegaard
@KirkegaardEmil

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Emil O W Kirkegaard

@KirkegaardEmil

#psychology #genomics #hbd #rstats #statistics #genomics #transhumanism #dataviz #openscience #psychometrics @OpenPsychJour

Denmark
emilkirkegaard.dk
Joined January 2012

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    1. Emil O W Kirkegaard‏ @KirkegaardEmil 3 Nov 2016
      • Report Tweet

      Molecular Genetic Contributions to Social Deprivation and Household Income in UK Biobank. GREML h2 for S ≈ 22%. http://www.cell.com/current-biology/fulltext/S0960-9822(16)31119-8 …

      1 reply 0 retweets 1 like
    2. Emil O W Kirkegaard‏ @KirkegaardEmil 3 Nov 2016
      • Report Tweet
      Replying to @KirkegaardEmil

      Note: hilariously bad polygenic score validity. r ≈ .03. Using bad GWAS method with n=110k yields about nothing useful.

      1 reply 0 retweets 0 likes
    3. 𝔊𝔴𝔢𝔯𝔫‏ @gwern 3 Nov 2016
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      Replying to @KirkegaardEmil

      The GCTA is still there, though.

      2 replies 0 retweets 0 likes
    4. Emil O W Kirkegaard‏ @KirkegaardEmil 3 Nov 2016
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      Replying to @gwern

      Not even GREML-LDMS. :(

      1 reply 0 retweets 0 likes
    5. 𝔊𝔴𝔢𝔯𝔫‏ @gwern 3 Nov 2016
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      Replying to @KirkegaardEmil

      22% is fairly normal for a GCTA estimate. Ton of smaller ones in my WP article. Could be a lot worse.

      1 reply 0 retweets 0 likes
    6. Emil O W Kirkegaard‏ @KirkegaardEmil 3 Nov 2016
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      Replying to @gwern

      Yes, but I want them to be better methods. Why not LDAK? Why not GREML-LDMS? But it's a nice replication for the other findings.

      1 reply 0 retweets 0 likes
    7. 𝔊𝔴𝔢𝔯𝔫‏ @gwern 3 Nov 2016
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      Replying to @KirkegaardEmil

      Probably because the work was done a year ago and LDAK/LDMS are not widely or easily used and not considered required.

      1 reply 0 retweets 0 likes
      Emil O W Kirkegaard‏ @KirkegaardEmil 3 Nov 2016
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      Replying to @gwern

      Yes, plausible. Reminds me that you should publish that meta-analysis of GREML results, at least for the most important traits.

      5:38 PM - 3 Nov 2016
      1 reply 0 retweets 0 likes
        1. Emil O W Kirkegaard‏ @KirkegaardEmil 3 Nov 2016
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          Replying to @KirkegaardEmil @gwern

          publish = write a paper :P

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