@piffer_davide @KirkegaardEmil Thoughts on statistical approach in http://www.gwern.net/Statistical%20notes#dysgenics-power-analysis … ? Any libraries for directional selection power?
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@gwern @piffer_davide Another assumption made but not discussed is no restriction of range, which we know is true.
@gwern @piffer_davide Worse, restriction of range may correlate with age, and I'm not sure how that impacts results. Otherwise good work :)
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@KirkegaardEmil @piffer_davide That is serious. If older people get genome 4 medicine, young 4 curiosity - insta pseudo-eugenics/false null -
@gwern @piffer_davide Yes, it is a problem with the opt-in samples, e.g. 23andme. Is there some actually representative sample somewhere? -
@KirkegaardEmil @piffer_davide SSGAC might be representative. Dutch LifeLines Biobank and Health & Retirement Survey should be.
End of conversation
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