@KirkegaardEmil That sounds ultra-weird. Weren't we expecting OCEAN to be not nearly as polygenic as IQ due to balancing selection? No hits‽
GWAS for big E. 63k. No hits p<alpha. GCTA consistent with 0 (?!), but polgen scores show signal https://www.researchgate.net/publication/281713367_Meta-analysis_of_Genome-Wide_Association_Studies_for_Extraversion_Findings_from_the_Genetics_of_Personality_Consortium …
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@KirkegaardEmil After reading, not too impressed. GCTA was only 6k and not 63k? no wonder it's imprecise; still consistent with the earlier -
@gwern More strange that polygenic scores had predictive power in one validation sample but not the other: R2's of 5% vs 0% despite large N
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@KirkegaardEmil GCTA have had a hard time with personality. -
@JayMan471@KirkegaardEmil Is it because it's apparently partly non-additive, or something else? -
@SilverVVulpes Apparently not due to common variants.@KirkegaardEmil
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