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KirkegaardEmil's profile
Emil O W Kirkegaard
Emil O W Kirkegaard
Emil O W Kirkegaard
@KirkegaardEmil

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Emil O W Kirkegaard

@KirkegaardEmil

#psychology #genomics #hbd #rstats #statistics #genomics #transhumanism #dataviz #openscience #psychometrics @OpenPsychJour

Denmark
emilkirkegaard.dk
Joined January 2012

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    1. Jaime  👻‏ @drderringer Jul 24
      • Report Tweet

      Can’t stop thinking about how there is no sex difference in polygenic scores for height

      9 replies 5 retweets 30 likes
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    2. Jonatan Pallesen‏ @jonatanpallesen Jul 24
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      Replying to @drderringer @hbdchick

      I mean, given that PGS are based on autosomes, it's pretty obvious that there can't be gender differences in any PGS.

      3 replies 0 retweets 8 likes
    3. Emil O W Kirkegaard‏ @KirkegaardEmil Jul 25
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      Replying to @jonatanpallesen @drderringer @hbdchick

      Well, not for long since it resets every generation, but one could have them by stark differential mortality based on PGS. (if one Sparta style killed all the newborn boys with PGS below 50th centile)

      1 reply 0 retweets 1 like
    4. Davide Piffer‏ @DavidePiffer Jul 25
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      Replying to @KirkegaardEmil @jonatanpallesen and

      Sex dimorphism doesn't require sex chromosomes. Autosomal SNPs (with equal freqs by sex) can produce dimorphism via sex specific effects (usually due to gene expression interacting with hormones). Quite a few papers on this

      1 reply 0 retweets 1 like
    5. Jonatan Pallesen‏ @jonatanpallesen Jul 25
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      Replying to @DavidePiffer @KirkegaardEmil and

      We are discussing polygenic scores specifically.

      1 reply 0 retweets 0 likes
    6. Davide Piffer‏ @DavidePiffer Jul 25
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      Replying to @jonatanpallesen @KirkegaardEmil and

      Yes I know. So?!

      3 replies 0 retweets 0 likes
      Emil O W Kirkegaard‏ @KirkegaardEmil Jul 25
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      Replying to @DavidePiffer @jonatanpallesen and

      They usually define these without option for interactions and using autosomes only so the betas can't differ by sex.

      8:32 AM - 25 Jul 2019
      3 replies 0 retweets 0 likes
        1. Davide Piffer‏ @DavidePiffer Jul 25
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          Replying to @KirkegaardEmil @jonatanpallesen and

          Also, dimorphism isn't necessarily due to sex chromosomes, in some species:https://doi.org/10.1111/jeb.12596 …

          0 replies 0 retweets 2 likes
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        1. Davide Piffer‏ @DavidePiffer Jul 25
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          Replying to @KirkegaardEmil @jonatanpallesen and

          See Evidence for sex-specific genetic architectures across a spectrum of human complex traitshttps://doi.org/10.1186/s13059-016-1025-x …

          0 replies 0 retweets 1 like
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        1. Davide Piffer‏ @DavidePiffer Jul 25
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          Replying to @KirkegaardEmil @jonatanpallesen and

          Isn't that just a convention though? I have seen papers dealing with sex specific effects of autosomal SNPs.

          0 replies 0 retweets 0 likes
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