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KirkegaardEmil's profile
Emil O W Kirkegaard
Emil O W Kirkegaard
Emil O W Kirkegaard
@KirkegaardEmil

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Emil O W Kirkegaard

@KirkegaardEmil

#psychology #genomics #hbd #rstats #statistics #genomics #transhumanism #dataviz #openscience #psychometrics @OpenPsychJour

Denmark
emilkirkegaard.dk
Joined January 2012

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    1. Emil O W Kirkegaard‏ @KirkegaardEmil Mar 11
      • Report Tweet

      Are there any follow-ups to the study that used natural variation in sibling relatedness to infer heritability? Hard to find so many siblings, so UKBB has 20k or something, so haven't someone done this phenome-wide yet? #genomics https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.0020041 … https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.0020041 …pic.twitter.com/Bm64zdyOWj

      1 reply 4 retweets 17 likes
    2. 𝔊𝔴𝔢𝔯𝔫‏ @gwern Mar 11
      • Report Tweet
      Replying to @KirkegaardEmil

      There's the RDR variant: https://www.gwern.net/docs/genetics/heritable/2018-young-2.pdf …

      1 reply 0 retweets 2 likes
    3. Emil O W Kirkegaard‏ @KirkegaardEmil Mar 11
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      Replying to @gwern

      Yeah, but I was thinking just a straight sibling approach, very clean but needs a big sample.

      1 reply 0 retweets 0 likes
    4. 𝔊𝔴𝔢𝔯𝔫‏ @gwern Mar 11
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      Replying to @KirkegaardEmil

      Ask 23andMe to do it. :) All those siblings and phenotypes...

      1 reply 0 retweets 1 like
      Emil O W Kirkegaard‏ @KirkegaardEmil Mar 11
      • Report Tweet
      Replying to @gwern

      Emil O W Kirkegaard Retweeted Emil O W Kirkegaard

      23andme busy making a shit T2D predictor.https://twitter.com/KirkegaardEmil/status/1105207013137625089 …

      Emil O W Kirkegaard added,

      Emil O W Kirkegaard @KirkegaardEmil
      23andme has a new whitepaper on diabetes type 2 prediction. It's pretty shitty though, AUC of 0.65 in Europeans, even less in others. Probably not genomic disease prediction is worth using if AUC < 0.80 / 10% variance. #genomics https://blog.23andme.com/health-traits/type-2-diabetes/ … https://permalinks.23andme.com/pdf/23_19-Type2Diabetes_March2019.pdf … pic.twitter.com/CjZzM2sKTd
      7:30 PM - 11 Mar 2019
      0 replies 0 retweets 1 like

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