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@KirkegaardEmil Also check out https://www.preprints.org/manuscript/201706.0039/v1 … . Back in 2017 when you were still advocating using full GWAS set! "The present approach maximizes signal by focusing on the average signal produced by each SNPs, rather than the sum of the signal produced by all the SNPs.
There is more signal in the full PGS, as clearly shown by the validity. You are conflating issues of pop strat and signal.
I am talking about selection signal. Why would I look for stratification signal?
The significant SNPs have more selection signal than the full GWAS SNPs.
You keep making the mistake of confusing average signal per SNP with sum total signal. For selection signal only the former matters
Signal and validity are not the same thing
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