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KirkegaardEmil's profile
Emil O W Kirkegaard
Emil O W Kirkegaard
Emil O W Kirkegaard
@KirkegaardEmil

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Emil O W Kirkegaard

@KirkegaardEmil

#psychology #genomics #hbd #rstats #statistics #genomics #transhumanism #dataviz #openscience #psychometrics @OpenPsychJour

Denmark
emilkirkegaard.dk
Joined January 2012

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    Emil O W Kirkegaard‏ @KirkegaardEmil Feb 13
    • Report Tweet

    Emil O W Kirkegaard Retweeted Patrick Phillips

    I wonder who has been saying this for a while? :)https://twitter.com/granex/status/1095272687197450240 …

    Emil O W Kirkegaard added,

    Patrick Phillips @granex
    Maier: Conundrum: if you fully correct for all stratification, then you will lose selection signal, since selection generates stratification. Instead of PCA, use stricter genome-wide significance signal, use sibling estimates, or separate GWAS and prediction populations. #adapt19
    Show this thread
    11:47 AM - 13 Feb 2019
    • 4 Likes
    • Francisco Boni mrbf Richard Harper
    1 reply 0 retweets 4 likes
      1. New conversation
      2. Davide Piffer‏ @DavidePiffer Feb 13
        • Report Tweet
        Replying to @KirkegaardEmil

        Hmm well I did but someone called Emil scorned me for ages for using GWAS significant hits only, arguing for using the entire set, contrary to what appears to be true

        1 reply 0 retweets 1 like
      3. Emil O W Kirkegaard‏ @KirkegaardEmil Feb 13
        • Report Tweet
        Replying to @DavidePiffer

        I don't know nothing about that! Your reasoning was mistaken (you were arguing along lines of repeated replication not pop strat issues), but the conclusion turns out to be a good idea. Better yet is to use Lee's putative causal snps, as you did, and that changed not much at all.

        3 replies 0 retweets 1 like
      4. Davide Piffer‏ @DavidePiffer Feb 14
        • Report Tweet
        Replying to @KirkegaardEmil

        I repeatedly insisted that using the full set of Gwas SNPs would dilute the selection signal and argued for using the Gwas significant hits. It is written all over my preprints and Woodley can testify how many times we talked about it. You just didn't get the concept straight

        0 replies 0 retweets 0 likes
      5. End of conversation

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