The strongest variant for Alzheimer's is also linked to higher IQ (APOE). Selecting against Alzheimer is selecting for IQ. Selection is always multi-dimensional due to ubiquitous genetic correlations, but they mostly benevolent.https://www.technologyreview.com/s/612494/despite-crispr-baby-controversy-harvard-university-will-begin-gene-editing-sperm/ …
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Pleiotropy in human diseases is mostly beneficial ('everything good goes together, everything bad likewise'). Check the multivariate selection analyses here. https://www.gwern.net/Embryo-selection …
11:22 AM - 30 Nov 2018
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