New paper on topichttps://www.biorxiv.org/content/early/2018/11/28/478776 …
Show this thread
The strongest variant for Alzheimer's is also linked to higher IQ (APOE). Selecting against Alzheimer is selecting for IQ. Selection is always multi-dimensional due to ubiquitous genetic correlations, but they mostly benevolent.https://www.technologyreview.com/s/612494/despite-crispr-baby-controversy-harvard-university-will-begin-gene-editing-sperm/ …
-
-
Thanks. Twitter will use this to make your timeline better. UndoUndo
-
-
-
This Tweet is unavailable.
-
Pleiotropy in human diseases is mostly beneficial ('everything good goes together, everything bad likewise'). Check the multivariate selection analyses here. https://www.gwern.net/Embryo-selection …
End of conversation
-
-
-
Linked doesn't imply positive association.
End of conversation
New conversation -
-
-
It must be selected for because of some benefit
Thanks. Twitter will use this to make your timeline better. UndoUndo
-
-
-
longevity versus economic and creative output. Textbook example of antagonistic pleiotropy.
- 2 more replies
New conversation -
-
-
Genes are 'for' traits?
- 5 more replies
New conversation -
-
-
you mean selecting against IQ, right?
Thanks. Twitter will use this to make your timeline better. UndoUndo
-
-
-
Also, everyone has an apoE allele. It’s the ε4 SNP that is responsible for bot polymorphic traits.
Thanks. Twitter will use this to make your timeline better. UndoUndo
-
Loading seems to be taking a while.
Twitter may be over capacity or experiencing a momentary hiccup. Try again or visit Twitter Status for more information.