Here it comes: *Multiple* injections of CRISPR required to developing embryos to reduce mosaicism.
Replying to @antonioregalado
One can probably also remove natural mosaicism with CRISPR as well, and fix some aneuploidies including Down's.https://genomebiology.biomedcentral.com/articles/10.1186/s13059-017-1354-4 …
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