Sahib Khalsa

@KhalsaLab

Psychiatrist and neuroscientist studying the role of interoception in mental health. Director of Clinical Studies, Laureate Institute for Brain Research.

Tulsa, Oklahoma
Vrijeme pridruživanja: studeni 2019.

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  1. proslijedio/la je Tweet
    prije 17 sati

    Makes me so happy that magazine have just written a piece on interoception! Never would have imagined it, espeically as when I started in this field no-one was really talking about it. Featuring the wonderful researchers &

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  2. proslijedio/la je Tweet

    Interoception research in by freaturing research by & yous truly Can You Feel Your Heartbeat? The Answer Says a Lot About You via

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  3. proslijedio/la je Tweet
    30. sij

    Almost all speakers of the are confirmed! Check out this year's speakers! Registration will open soon.

    , , i još njih 7
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  4. proslijedio/la je Tweet
    28. sij

    Here is some nice work from our LIBR group and developing a graphical interface to capture the longitudinal aspects of psychopathology for psychiatric disorders:

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  5. 24. sij

    “I was now on a dark path, unsettled by a future filled with big data and small comprehension.”

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  6. proslijedio/la je Tweet
    22. sij

    This is a great opportunity, we have lot's of multi-level data collected, so no publication lag, and a well-organized training framework:

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  7. proslijedio/la je Tweet
    16. sij

    Our 2nd insula paper is out in ! We found that insular cortex represents current bodily state AND uses external cues to “simulate” future changes to bodily physiology – “How do I feel?” + “How will this make me feel?” More in THREAD…1/7

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  8. 21. sij

    The findings could have implications for both the acquisition and extinction of associative learning in psychiatric disorders. What if disordered eating could be partially explained by SFO- and AgRP-induced hyperpolarization of insular neurons during quenched/sated states?

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  9. 21. sij

    Some speculation: the additional SFO input during quenched/sated states may represent a non-gustatory influence on control of eating behavior, i.e. a potential mechanism by which allostatic regulation could occur. The exaggerated responses across both conditions is hard to ignore

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  10. 21. sij

    Given cross-species differences in insular cortex cytoarchitecture, I wonder if the ability to model insular neurons heavily depends on where you measure from. Mouse analogs to posterior vs. anterior insula? Simultaneous recordings?

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  11. 21. sij

    The inability to predictably model all recorded insular cortex neurons (Fig 2B/C) is not that surprising to me. It may reflect the fact that insular cortex is more polymodal than V1, as it will likely be mapping signals from cardiac, respiratory, GI, GU, chemosensory sources etc.

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  12. 21. sij

    Analysis & exclusion of arousal-related and time-related factors differentiated the findings from 1) insula's role in mapping autonomic arousal (see our most recent fMRI paper ) & 2) time perception, which has also been linked to insula ()

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  13. 21. sij

    They observed distinct coding of hunger and thirst within SFO/MnPO and AgRP neurons is an exciting observation. SFO-activation induced drinking in the quenched state, in conjunction with insular responses, powerfully demonstrates the interoceptive function of this neural circuit

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  14. 21. sij

    New interoception paper hot off the press from Mark Andermann's group : First, this is a super-cool experiment and methodology. The causal power with manipulating neural circuits related to interoception is unparalleled.

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  15. proslijedio/la je Tweet
    23. pro 2019.
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  16. 11. pro 2019.

    Stellar findings kicking off the 2019 hot topics about direct connections between mouse insular cortex and amygdala subregions from and the role of mouse insula in conditioned overconsumption . A hot topic 1-2 punch!

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  17. 5. pro 2019.

    Thanks Sarah! Stay tuned, and looking forward to seeing you at the interoception meeting.

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  18. 4. pro 2019.

    Interesting new paper reporting the development of a novel stimulator that induces somatic chills. Is interoceptive neuroscience gaining momentum?

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  19. 4. pro 2019.

    Looking forward to participating in this exciting meeting on next year. It promises to be a great follow up to this year's workshop “The Science of Interoception and Its Roles in Nervous System Disorders” (see the whole thing ).

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