We're now tracking Lassa virus evolution and spread at https://nextstrain.org/lassa/ . Includes recent genomes from Nigeria shared by Christian Happi, @acegid and @sabeti_lab.pic.twitter.com/EitrZuUHqP
Deze collectie tonen
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yes. these long branches are not smth TreeTime was made for... also the clock signal is weak (->inaccurate rate) and many sites saturated. age of deep splits likely very different.
Yeah, lack of clock is definitely an issue. In BEAST, also very sensitive to model choice - e.g. pop model, codon partitioning, etc. Tricky virus for sure (even more so with larger dataset compares to our 2015 paper).
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but we don't know the truth, right?
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