Interesting new Lassa virus lineage out of Togo. Is this a recombinant? https://wwwnc.cdc.gov/eid/article/24/3/17-1905_article …pic.twitter.com/sa4eHWS9Pi
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Figure shows evidence of reassortment, yes, but it's noisy for GPC and NP trees. Those should have been combined into a single tree.
. The former is pretty unlikely, the latter plausible given the bipartite genome.Yup, makes more sense to look at segments individually (to test for reassortments) - unless you have reason to believe recombination could have occured (we see very little / no evidence for that in our 2015 paper)
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Until there might be some functional studies it looks less interesting to me. Yes, the L and S segment phylogeny have shifted slightly, which could be an inner-LASV reassortment, but it's all still well within LASV strains, suggesting nothing unusual yet
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I’m not suggesting there’s anything functional going on here, only that being a reassortant - given the geographical range of the virus - is interesting.
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