Kristian G. AndersenGeverifieerd account

Indeed. But much too risky to hope for that (esp. given recent pubs). Extensive studies needed asap. No taking back a vacc.

this is true. But isn't it fair to assume that lack of "severe" disease as result of Zika introduction in Brazil would suggest

that potential Ab enhancement of Zika is not too clinically relevant, so that Dengue protection outweighs this concern?

In my opinion no. Plausible links for MicroC and GBS to Dengue have been made. Again, once you vacc. there's no going back.

I think the prudent thing would be is to wait until (a) more research comes in, or (b) herd immunity to ZIKV.

so, possibility for vaccine trials in areas where Zika was/highly prevalent so that you assume people were exposed?

Exactly. IMO required at this stage - we know too little with Flavis.

Or at least wait for NHP experiments to understand potential interactions more.