This is a nice read - but note, n=1 (out of n=45). One thing I found interesting that the article didn't explain in detail, is the fact that the subject appeared to develop a severe allergic reaction to the booster. https://www.statnews.com/2020/05/26/moderna-vaccine-candidate-trial-participant-severe-reaction/ … 1/
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Neutralizing antibodies to SARS and MERS will decline after a couple/few years so lasts much longer than CC CoVs - not lifelong, mind you, but longer. Do those nAbs lead to sterilizing immunity? Dunno, but not unreasonable to think. So I go with that until proven otherwise
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I’m with you. Plus nAbs titers aside, memory B cells+T cells, I think there’s immunity there. Entirely sterilizing I don’t know, but I’d be very very surprised if there was no protection.
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Okay I think we’re on a similar page! SARS didn’t ultimately cause so many infections to be fair, but certainly now even a single documented re-infection would be front page news, and there’s no news.
Bedankt, Twitter gebruikt dit om je tijdlijn te verbeteren. Ongedaan makenOngedaan maken
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Het laden lijkt wat langer te duren.
Twitter is mogelijk overbelast of ondervindt een tijdelijke onderbreking. Probeer het opnieuw of bekijk de Twitter-status voor meer informatie.
. Many compare SARS-2 immunity to common cold bCoVs, but I don't think we can do that-very different infections. For SARS and MERS we don't understand immunity, but I haven't heard of a SARS reinfection and SARS-2, much more like that