A really good overview of antigen rapid diagnostic tests - these will transform our ability to test for #COVID19.
https://www.sciencemag.org/news/2020/05/coronavirus-antigen-tests-quick-and-cheap-too-often-wrong …
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A few things though: “What everyone wants is for a test to be cheap, accurate, and fast,” says Geoffrey Baird, a laboratory medicine specialist at the University of Washington, Seattle. “You can only ever have two of those.” Not true - e.g. Ebola: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(15)61042-X/fulltext … 2/4
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A lot of mistakes in this paragraph - all of this simply isn't true because of mixing of sensitivity/specificity + calc mistakes. For these types of tests, we assume high specificity, but lower sensitivity - but that doesn't lead to the results mentioned in this paragraph. 3/4pic.twitter.com/BuYppZFRH0
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"Given how readily the SASR-CoV-2 spreads, “a misdiagnosis is worse than no diagnosis,”" I disagree with this - for the intended POC usage of RDTs, this is less of a concern. I'm very optimistic about RDTs - they won't be perfect, but they'll make a big difference 4/4
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