Kristian G. AndersenGeverifieerd account

Thanks for the talk, I really enjoyed it! This was certainly the most stunning slide. I had thought that the previous development of a (multiple?) MERS vaccine allowed for the more optimistic (18 mo) timeline on the SARS-CoV-2 vaccine.

Thanks. And yes, I considered the fact that previous developments on SARS / MERS helps us, but the main issue here is that those vaccines have really conflicting data (e.g., having to deal with ADE). Vaccines typically take 10+ years, so if we can do it in 4, that'd be win(ish).

I think *if* the mRNA vaccines work we can have a vaccine faster than your timeline given how they're being fast-tracked. Not sure how production scales on those tho. I guess overall I might say quicker than year 4. The CoV field veterans seem fairly unconcerned about ADE.

I’m similarly not hearing great concern about immune enhancement from the folks I am interacting with. Vaccine working groups organized by WHO. Certainly something to track, but it hasn’t been the main topic of conversation. (But I’m also not an immunologist.)