Since I have probably gotten these questions a thousand times by now, let me just do a quick summary: 1. Is it mutating? Yes. It's normal. 2. Did the epidemic take off in the market? Yes. It's uncontroversial. 3. How do you know? See 1. Apply math. More to come.
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Als antwoord op @K_G_Andersen @angie_rasmussen
Regarding #2, it took off in the market, but my understanding was that evidence pointed to it not originating from there. Is that correct?
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Correct. The linked lancet article demonstrated that the first case seen in Wuhan did not have links to the seafood market. This is a graph from the article. Spread uncontroversially took off in the market but may not be the source. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30183-5/fulltext …pic.twitter.com/koEYqdZ5lw
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Als antwoord op @jeremydratcliff @BigFernowski en
A bit of a stretch based on one case? That case could have been infected by casual contact with someone with market exposure and a mild case, on public transit or almost anywhere. That carrier may have recovered and never gone to hospital or been tested. Sampling in market was +.
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Als antwoord op @stewak2 @jeremydratcliff en
33% of the cases in December had no known contact with the seafood market (or other wet market) and as you can see on the graph 75% of the earliest 4 cases had no contact with animal markets. So likely the virus was circulating among human population weeks before market outbreak
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As far as I know no infected animals at the market have yet been identified, and not much is known about the environmental sampling other than significant contamination was confirmed at seafood market. It seems hard to square that fact with the high number of unconnected cases.
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That data also won’t ever be obtained as the market was disinfected once it was shuttered in December. It was the correct move from a public health perspective, but will frustrate ecologists and others trying to identify the source
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Als antwoord op @jeremydratcliff @bleidl en
Not sure about that. I would guess they will run down all the suppliers to the suspect vendors in western side of market. Something like that was done with SARS. Might get “lucky”.
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Yeah, I’m also not totally convinced they won’t be able nail down the (likely) intermediate host. Some very resourceful people working on this I’m sure... Might have a sequence from it within a month 
Het laden lijkt wat langer te duren.
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