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I’m definitely not defending their choice of words. However, the mention in the article of GP 82 made me want to check if it was showing up in DRC.
Ah, okay. Yeah, no sign of GP-A82V, although, of course, that doesn't mean that other adaptive substitutions aren't present in the population (but if they are, as we both agree on, has nothing to do with "becoming more deadly").
Yep. Agreed. The normal expectation here would be a trade-off between within-host selection for better cell-to-cell replication against between-host selection for increased transmission (which could be achieved through attenuation).
Makes one wonder what impact the widespread use of a vaccine during this outbreak is having on selection of changes incurred through the different transmission chains...if any...wonderful that a question like this is even approachable now...
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