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Question - latency up to beginning of outbreak makes sense, but that hypothesis can be directly tested (given data). I.e., what's the clock within each of the two DRC outbreaks? I assume probably the same as other outbreaks? (i.e., close to larger tree).
If yes, then we know that latency is a function of the (reservoir?) host, and not actually something intrinsic to a particular (DRC) Ebola virus lineage. Completely what we would expect, but nice to explicitly test (especially given, ehm, certain papers...).
I think it may be a mechanism that the virus has used to persist in the reservoir - sweeps through a population (roost?) and if it isn’t able to move on to another, then much later it can re-emerge from an older bat to infect all of the new naive bats that have been accumulating.
Yup, I think that's totally reasonable. I *do* wonder about the potential for an intermediary (amplifying? 'adapting'?) host too though - e.g., great apes. Could the virus create latency in bats more generally, but then bounce between species (prior to outbreaks?).
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